Sökning: "inflammatory cells"

Visar resultat 1 - 5 av 1693 avhandlingar innehållade orden inflammatory cells.

  1. 1. Astroglial Cells : Role in Neurodegenerative-Inflammatory Processes in the Central Nervous System

    Författare :Gun Eriksson; Karl Åkerman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Inflammatory processes, mediated by the pro-inflammatory cytokines interleukin (IL) -1a/b, tumor necrosis factora(TNFa), IL-6 and excitotoxic actions of glutamate, are proposed to be implicated in neurodegenerative diseases, such as Alzheimer's disease.A neurotoxic fragment ofb-amyloid,bA25-35, was shown to induce a reactive phenotype of primary astrocytes and microglial cells in a time-dependent manner. LÄS MER

  2. 2. Mucosal dendritic cells in inflammatory bowel disease

    Författare :Sa'ad Yislam Salim; Johan D. Söderholm; Mary jo Wick; Linköpings universitet; []
    Nyckelord :Blood; Crohn s disease; dendritic cells; E. coli; FACS; follicle-associated; epithelium; human; ileum; mixed lymphocyte reaction; permeability; Peyer s patches; SAMP1 YitFc; Ussing chambers; villous epithelium; MEDICINE; MEDICIN;

    Sammanfattning : Crohn's disease, a chronic inflammation of the bowel, is a multi-factorial condition where uncontrolled immune responses to luminal bacteria occur in genetically predisposed individuals. The first observable clinical signs are small ulcers that form at a specialised form of epithelium, follicle-associated epithelium (FAB). LÄS MER

  3. 3. Commensal microbes, immune reactivity and childhood inflammatory bowel disease

    Författare :Cecilia Barkman; Göteborgs universitet; []
    Nyckelord :Inflammatory bowel disease; IBD; Pediatric; Childhood; Microbiota; T cells; B cells; cytokine; IL-12; monocytes; phagocytosis; intracellular signaling pathway; Crohn s disease; ulcerative colitis; children; flora;

    Sammanfattning : Inflammatory bowel disease (IBD) is characterized by chronic and relapsing intestinal inflammation of unknown etiology, but immune activation by the commensal microbiota probably plays a major role. The two major categories of IBD are ulcerative colitis and Crohn’s disease. LÄS MER

  4. 4. Bacterial Regulation of Peripheral Immunity : Mechanistic insights from lactobacilli and Staphylococcus aureus

    Författare :Manuel Mata Forsberg; Eva Sverremark-Ekström; Monika Brunner-Weinzierl; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immune regulation; Cytokines; T cells; gamma-delta T cells; MAIT cells; NK cells; Lactobacillus; Staphylococcus aureus; staphylococcal enterotoxins; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : There is a constant cross-talk between our immune system and the colonizing microbiota. The gut resident bacteria produce a broad range of molecules with regulatory activities in both local and distal tissues. Staphylococcus (S. LÄS MER

  5. 5. Mast Cells as Sentinels : Role of serglycin and mast cell proteases in infection and inflammation

    Författare :Ananya Roy; Magnus Åbrink; Olaf Utermöhlen; Uppsala universitet; []
    Nyckelord :mast cells; serglycin; chymase; infection; parasite; Immunologi; Immunology;

    Sammanfattning : Mast cells (MCs), normally classified into connective tissue MCs and mucosal MCs, are highly granulated cells found in the interface between the interior and the exterior environment of our body, e.g. skin, airways and gastro-intestinal tract. LÄS MER