Sökning: "immature"

Visar resultat 1 - 5 av 363 avhandlingar innehållade ordet immature.

  1. 1. The role of bacterial endotoxin in the immature brain

    Författare :Saskia Eklind; Göteborgs universitet; []
    Nyckelord :lipopolysaccharide; hypoxia-ischemia; immature; temperature; cerebral blood flow; blood glucose; inflammation; apoptosis; microarray; preconditioning;

    Sammanfattning : Aim: Epidemiological evidence suggests that infections may increase the vulnerability of the immature brain to further insults. The aim of this thesis was to investigate the role of bacterial endotoxin (lipopolysaccharide, LPS) on hypoxic-ischemic (HI) injury in the immature rat brain, and to evaluate possible underlying mechanisms of increased sensitivity. LÄS MER

  3. 2. Inflammation and neuroprotective strategies in the immature brain after hypoxic-ischemic brain injury

    Författare :Pernilla Svedin; Göteborgs universitet; []
    Nyckelord :hypoxia-ischemia; LPS; immature; brain; inflammation; NAC; melatonin; G-2mPE; MMP-9; MMP-12;

    Sammanfattning : Perinatal brain injury, as a result of hypoxia-ischemia (HI) or infection/HI, is a major cause of acute mortality and neurological morbidity in infants and children. The mechanisms of perinatal HI are not fully understood, which makes it difficult to find effective treatment. LÄS MER

  4. 3. Very preterm infants and later lung function - impact of perinatal inflammation, club cell secretory protein and bronchopulmonary dysplasia

    Författare :Cecilia Hagman; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Preterm children; perinatal inflammation; club cell protein CC16 ; bronchopulmonary dysplasia; lung function; Respiratory health; immature;

    Sammanfattning : .... LÄS MER

  5. 4. Inflammation in the immature brain: The role of Toll like receptors

    Författare :Linnea Stridh; Göteborgs universitet; []
    Nyckelord :hypoxia-ischemia; immature brain; inflammation; innate immunity; Toll-like receptors;

    Sammanfattning : Infection/inflammation and/or hypoxia-ischemia (HI) are major causes of perinatal brain injury. Toll-like receptors (TLRs), important components of innate immunity, have been shown to be involved in brain injury, both after infectious and endogenous, non-infectious, stimuli. LÄS MER

  7. 5. Hypoxic-ischemic injury in the immature brain. Role of mitochondria, caspases and NMDA receptors

    Författare :Malgorzata Puka-Sundvall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neonatal; immature rats; hypoxia-ischemia; brain damage; calcium; mitochondria; permeability transition; apoptosis; caspase-3; NMDA receptor; electron microscopy;

    Sammanfattning : .... LÄS MER