Sökning: "gold sodium thiomalate"

Hittade 4 avhandlingar innehållade orden gold sodium thiomalate.

  1. 1. Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation

    Författare :Sofia Ernestam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Rheumatoid arthritis; cytokines; gold sodium thiomalate; TNF-antagonists;

    Sammanfattning : Rheumatoid arthritis (RA) is a systemic inflammatory disease primarily affecting the joints. In the pathogenesis several cells of the immune systeme and messengers of the immune systeme, cytokines, are important. LÄS MER

  3. 2. Endothelial cell interactions with neutrophils : studies of adhesion and effects of lipoxygenase metabolites and antirheumatic drugs

    Författare :Mikael Heimbürger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adhesion; auranofin; endothelium; gold sodium thiomalate; leukotrienes; lipoxins; neutrophils; PPAR; prednisolone;

    Sammanfattning : Inflammation is a process of vital importance in the defence and elimination of microorganisms as well as in the repair of the damaged tissue. However, inadequate or excessive inflammation leads to inflammatory diseases such as rheumatoid arthritis. LÄS MER

  4. 3. Studies of pharmacological interventions and pathogenesis of rheumatoid arthritis

    Författare :Jon Lampa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is a systemic inflammatory disease primarily affecting the joints. The chronic inflammation frequently results in joint destruction and various forms of physical impairment. LÄS MER

  5. 4. Multiple roles of HMGB1 in clinical and experimental arthritides

    Författare :Hanna Schierbeck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammation can be infectious and/or sterile depending on the initiating event. The proinflammatory mediator High mobility group box protein 1 (HMGB1) is a nuclear protein released from cells during both sterile and infectious inflammation and once extracellular, initates and potentiates inflammation by inducing cytokine production and by recruiting inflammatory cells. LÄS MER