Sökning: "gel contraction"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden gel contraction.

1. 1. Integrin αVβ3-Directed Contraction by Connective Tissue Cells : Role in Control of Interstitial Fluid Pressure and Modulation by Bacterial Proteins

   Författare :Åsa Lidén; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; interstitial fluid pressure; collagen gel contraction; integrin αVβ3; septic shock; fibronectin; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : This thesis aimed at studying mechanisms involved in control of tissue fluid homeostasis during inflammation.The interstitial fluid pressure (PIF) is of importance for control of tissue fluid balance. A lowering of PIF in vivo will result in a transport of fluid from the circulation into the tissue, leading to edema. LÄS MER

3. 2. Extracellular Matrix and Actin Cytoskeleton - the Control Unit of Interstitial Fluid Volume

   Författare :Vahid Reyhani; Kristofer Rubin; Markella Ponticos; Uppsala universitet; []
   Nyckelord :Collagen; fibrin; integrins; PDGF-BB; gel contraction; fluid homeostasis; interstitial fluid pressure; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : The regulation of fluid (water) volume in the body is crucial for tissue homeostasis. The interstitial fluid, which comprises almost 20% of the body fluid, is stored in the loose connective tissue and its volume is actively regulated by components of this tissue. LÄS MER

4. 3. Carbothermal synthesis of nano-structured metal, carbides and nitrides, using solution processed precursors; from precursor to product

   Författare :Sarmad Naim Katea; Gunnar Westin; Hilmar Vidarsson; Sanjay Mathur; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solution-based chemical processing; sol-gel; ceramic powders; transition metal carbides and nitrides; sintering; nickel binder; mechanical properties; Chemistry with specialization in Inorganic Chemistry; Kemi med inriktning mot oorganisk kemi;

   Sammanfattning : This thesis describes how solution chemical based carbothermal syntheses can be used for the synthesis of nanostructured zirconium carbide and nitride nanophase powders as well as a nickel-metal coating on NbC for use as a sintering agent. The focus is on the development of novel synthesis routes using atomic or small nanoscale level mixing of the metal oxide and carbon source in the starting precursors, enabling the use of lower synthesis temperatures and non-agglomerated nanosized powders. LÄS MER

5. 4. Intra- and Extracellular Modulation of Integrin-directed Connective Tissue Cell Contraction

   Författare :Tijs van Wieringen; Kristofer Rubin; Anders Arner; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Interstitial fluid pressure; PDGF-BB; bacterial proteins; αVβ3 integrin; cytoskeleton; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : All blood vessels in the microvasculature are embedded in loose connective tissue, which regulates the transport of fluid to and from tissues. The intersti-tial fluid pressure (IFP) is one of the forces that control this transport. LÄS MER

7. 5. Functional Studies of Collagen-Binding Integrins α2β1 and α11β1 : Interplay between Integrins and Platelet-Derived Growth Factor Receptors

   Författare :Gunilla Grundström; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : Integrins are heterodimeric cell surface receptors, composed of an α- and a β-subunit, which mediate cell-extracellular matrix (ECM) interactions. Integrins mediate intracellular signals in response to extracellular stimuli, and cooperate with growth factor and other cytokine receptors. LÄS MER