Sökning: "cultured tumor cells"

Visar resultat 21 - 25 av 110 avhandlingar innehållade orden cultured tumor cells.

1. 21. Toxicological aspects of bile acids and human fecal water on cultured human colon carcinoma cells

   Författare :Björn Glinghammar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Colorectal tumorigenesis involves activation of mutations in proto-oncogenes, such as ras and c-myc, as well as mutations that inactivate tumor suppressor genes including the APC and the p53 gene. These genetic events, in turn, lead to epigenetic changes in signal transduction pathways, which regulate processes such as cell proliferation, differentiation and apoptosis. LÄS MER

3. 22. The role of red blood cells in inflammation and remodeling

   Författare :Karin Fredriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Red blood cells; fibroblast; inflammation; remodeling; fibrosis;

   Sammanfattning : Besides being carriers of oxygen and carbon dioxide, red blood cells (RBCs) also have a scavenger function, binding inflammatory mediators to surface receptors. Animal and experimental models have suggested a role for RBCs in inflammatory and fibrotic responses and patients with idiopathic pulmonary hemosiderosis, a disease characterized by lung hemorrhage, frequently develop fibrosis. LÄS MER

4. 23. Platelet-activating factor, intestinal epithelial cells, and Chron's disease : An experimental study

   Författare :Bengt Kald; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Platelet-activating factor (PAF-acethcr, 1-0-alky l-2-acetyl-s n- glycero-3- phosphocholine), is a potent inflammatory mediator that can be formed by a variety of cells and tissues. In the present investigation, the content of PAFacether was determined in mucosal biopsies from the ileum and colon of patients with Crohn's disease and control patients. LÄS MER

5. 24. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection

   Författare :Sofia Nordling; Peetra Magnusson; Paul Kubes; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial cells; Thrombosis; Innate immunity; Immunothrombosis; Thromboinflammation; Immunologi; Immunology;

   Sammanfattning : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. LÄS MER

7. 25. Mechanisms for and Effects of Airway Epithelial Damage in Asthma

   Författare :Anne-Jacqueline Relova; Eythor Björnsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; asthma; airways; cytokines; epithelium; tight junctions; mast cells; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

   Sammanfattning : The airway epithelium plays a crucial role in protecting the underlying connective tissue (CT) from noxious agents. Damage and shedding of the epithelium are observed in the airways of asthma, cystic fibrosis and rhinitis patients. LÄS MER