Sökning: "chemokines"

Visar resultat 6 - 10 av 271 avhandlingar innehållade ordet chemokines.

  1. 6. On the role of mast cells in chemokine-induced leukocyte recruitment

    Författare :Yusheng Wang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokines; mast cells; TNF-alpha; dexamethasone; P-selectin; E-selectin; activation; Medicine human and vertebrates ; endothelial cells; adhesion; Neutrophil; Medicin människa och djur ; recruitment;

    Sammanfattning : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. LÄS MER

  3. 7. On airway host defence during allergic inflammation

    Författare :Anele Gela; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

    Sammanfattning : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. LÄS MER

  4. 8. Antibacterial peptides - key players in host defense at epithelial surfaces

    Författare :Mette Eliasson; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosa; epithelium; pharyngitis; Innate immunity; Streptococcus pyogenes; antibacterial peptides; IFN-gamma; CXCL9 MIG; chemokines;

    Sammanfattning : Innate host defense mechanisms at epithelial surfaces are important to prevent bacterial invasion. Streptococcus pyogenes, group A streptococcus (GAS), has an affinity for epithelial cells and cause pharyngitis. During streptococcal pharyngitis, high concentrations of the chemokines CXCL9/MIG, CXCL10/IP-10, CXCL11/I-TAC were found in tonsil fluid. LÄS MER

  5. 9. On Neutrophil and Platelet Adhesive Interactions in Septic Lung Injury

    Författare :Asad Muhammad; Kirurgi; []
    Nyckelord :Leukocytes; chemokines; platelets; lung; sepsis;

    Sammanfattning : Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. LÄS MER

  7. 10. Neutrophil recruitment in H. pylori induced inflammation: characterization of regulatory factors

    Författare :Mikael Innocenti; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; endothelial cells; neutrophils; monocytes; transendothelial; migration; chemokines; cytokines; adhesion molecules inflammation; LPS; CagPAI; VacA;

    Sammanfattning : Helicobacter pylori, a bacterium colonizing the human gastric mucosa, is strongly associatedwith the development of gastric and duodenal ulcers, as well as gastric, adenocarcinoma.Virtually all infected individuals develop active chronic gastritis characterized by a continousinfiltration of neutrophils as well as mononuclear cells. LÄS MER