Sökning: "allele"

Visar resultat 6 - 10 av 672 avhandlingar innehållade ordet allele.

1. 6. Accessing Genetic Variation by Microarray Technology

   Författare :Katarina Lindroos; Edwin Southern; Uppsala universitet; []
   Nyckelord :Medical sciences; microarrays; SNPs; minisequencing; four-colour detection; allele frequency; population study; evolutionary biology; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Microarray technology is a promising approach for the simultaneous analysis of multiple single nucleotide polymorphisms (SNPs), which are the most abundant form of genetic variation. In this thesis enzyme-assisted microarray-based methods were developed to improve the accuracy and genotype discrimination power of the current methods for SNP genotyping. LÄS MER

3. 7. Variation in Silene vulgaris and S. uniflora (Caryophyllaceae): genetic diversity, gene flow and habitat selection

   Författare :Helena Runyeon; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; taxonomy; Systematic botany; seed shapes; morphology; allele frequencies; hybridization; immigration history; allozymes; genetic diversity; geographic variation; Silene; Caryophyllaceae; phytogeography; chemotaxonomy. Physiology of nonvascular plants; Systematisk botanik; taxonomi; morfologi; kemotaxonomi. Växters fysiologi inte kärlväxter .;

   Sammanfattning : Genetic and morphometric variation was studies in the three closely-related taxa Silene vulgaris (a widespread weed), S. uniflora ssp. uniflora (restricted to coastal habitats) and S. uniflora ssp. LÄS MER

4. 8. Genetics and Expression of Glycosphingolipids in the P1PK and GLOB Histo-Blood Group Systems

   Författare :Julia Westman; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glycosphingolipid; glycosyltransferase; null allele; GLOB; P1PK; Blood group;

   Sammanfattning : The glycosphingolipid (GSL) antigens in the clinically important P1PK and GLOB blood group systems are present on erythrocytes as well as other tissues and are so-called histo-blood group antigens. Blood group antigens of carbohydrate nature are products of enzymes, so-called glycosyltransferases, adding sugars in a step-wise manner to an acceptor substrate. LÄS MER

5. 9. Bayesian inference for detection problems in biology

   Författare :Ronny Hedell; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PCR; Bayesian inference; Forensic DNA analysis; Syndromic surveillance; Bacillus anthracis; Markov chain Monte Carlo; Allele dropout; Bacillus anthracis;

   Sammanfattning : This thesis is about different kinds of detection problems in biology: detection of DNA sequences in crime scene samples, detection of harmful bacteria in feed and food stuff and detection of epidemical diseases in animal populations. In each case, biological data is produced or collected in order to determine which DNA sequences, bacteria types or diseases are present, if any. LÄS MER

7. 10. Statistical Methods for Genome Wide Association Studies

   Författare :Malin Östensson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genome Wide Association Studies; gene-gene interactions; Genotype imputation; allele sharing; haplotype sharing; Single Nucleotide Polymorphism; Celiac Disease; haplotype sharing;

   Sammanfattning : This thesis focus on various statistical methods for analyzing Genome Wide Association data. The thesis include four papers, three of them considers the analysis of complex traits, and the last one a method for analyzing mendelian traits. LÄS MER