Sökning: "Yuan Zhuang"

Hittade 1 avhandling innehållade orden Yuan Zhuang.

1. 1. Regulation of B cell development by antigen receptors

   Författare :Jannek Hauser; Thomas Grundström; Yuan Zhuang; Umeå universitet; []
   Nyckelord :calcium; calmodulin; e-proteins; E2A; B cell development; antigen receptor signaling; surrogate light chains; RAG; allelic exclusion; V D J recombination; AID; negative feedback regulation; plasma cell differentiation;

   Sammanfattning : The developmental processes of lymphopoiesis generate mature B lymphocytes from hematopoietic stem cells through increasingly restricted intermediates. Networks of transcription factors regulate these cell fate choices and are composed of both ubiquitously expressed and B lineage-specific factors. LÄS MER