Sökning: "Tönis Lehto"

Hittade 1 avhandling innehållade orden Tönis Lehto.

  1. 1. Acylated cell-penetrating peptides for nucleic acid delivery

    Författare :Tönis Lehto; Ülo Langel; Eric Johnston; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell-penetrating peptides; nucleic acid delivery; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : In recent decades many new methods have been developed to cure or treat genetical disorders such as cancer, viral infections or inheritable diseases. The problem is that the nucleic acids and their synthetic analogs, oligonucleotides, are not able to cross the cell membrane due to their physicochemical properties like high negative charge and size. LÄS MER