Sökning: "Substitution effects"

Visar resultat 21 - 25 av 207 avhandlingar innehållade orden Substitution effects.

  1. 21. Effects of mutations in lymphoid malignancy and immunodeficiency disease

    Författare :Abdulrahman M Hamasy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mutations are responsible for causing various human diseases, including several types of cancer and immunodeficiency syndromes. They can either be involved directly in the pathogenesis of the disease or by influencing the treatment efficacy and cause failure of the patient’s response to a specific therapy by adapting the targeted cell to resist the treatment. LÄS MER

  3. 22. Effects of Molecular Architecture of Xylans on Material Properties

    Författare :Maria Gröndahl; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Xylans are among the most abundant polymers on earth. Nature has created xylans with different molecular structures in different plant species. This molecular architecture is not a coincidence but is tailored to create a particular desirable functionality. LÄS MER

  4. 23. Nitric oxide, formation and effects in the urogenital tract

    Författare :Ingrid Ehren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :urinary tract; male reproductive tract; nitric oxide; nitric oxide synthase; NADPH-diaphorase; smooth muscle; secretion; inflammation; sex hormones.STOCKHOLM 1996 ISB;

    Sammanfattning : The aim of the thesis was to study the formation and effects of nitric oxide (NO) in the human urinary tract and in the male reproductive organs. In the human upper and lower urinary tract NO synthase activity was studied via the formation of radiolabeled L-citrulline from L-arginine. LÄS MER

  5. 24. Swedish Pharmaceutical Benefit Reforms ?Analyses of implementation, pharmaceutical sales patterns and expenditures

    Författare :Karolina Andersson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmaceutical policy; health care reform; reimbursement; co-payment; reference-based pricing; generic substitution; drug cost; cost sharing;

    Sammanfattning : Background: Over the last few decades, the sales of prescription drugs have increased dramatically in many western countries; however, this increase requires individuals and society to bear larger economic consequences. To improve cost control for pharmaceuticals, several reforms attempt to reconcile the economic responsibility of the patients, prescribers and third party payers. LÄS MER

  7. 25. Perinatal nicotine exposure. Effects on the defense against hypoxia in lambs

    Författare :Ola Hafström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carotid body; nicotine; prenatal exposure delayed effects; respiration; respiratory mechanics; sudden infant death; smoking; tobacco;

    Sammanfattning : The aim of the present study was to evaluate whether perinatal nicotine exposure could impair cardiorespiratory defense mechanisms to hypoxia. The rationale for this approach is that exposure to tobacco smoke, particularly before birth, is a risk factor for the sudden infant death syndrome as well as for obstructive airway disease in childhood. LÄS MER