Sökning: "SCD-1"

Hittade 5 avhandlingar innehållade ordet SCD-1.

  1. 1. Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet

    Författare :Jonathan Cedernaes; Helgi B Schiöth; Robert Fredriksson; Anders Jacobsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adhesion GPCR; delta-5 desaturase; delta-6 desaturase; desaturase index; Diet-induced obesity; estimated desaturase activity; fatty acid composition; gas chromatography; gastrointestinal tract; G-protein coupled receptor; high-fat diet; intestine; linoleic acid; liver; mRNA expression; palmitoleic acid; plasma; phospholipids; proximodistal; RT-qPCR; solute carrier; SCD-1; SCD-16; SCD-18; stearoyl-CoA desaturase; subcutaneous adipose tissue; subsection; triacylglycerols.; Medical Genetics; Medicinsk genetik; Nutrition; Nutrition; Näringslära; Nutrition;

    Sammanfattning : The gastrointestinal tract (GIT) regulates nutrient uptake, secretes hormones and has a crucial gut flora and enteric nervous system. Of relevance for these functions are the G protein-coupled receptors (GPCRs) and the solute carriers (SLCs). LÄS MER

  3. 2. Dietary Fatty Acids and Inflammation : Observational and Interventional Studies

    Författare :Helena Bjermo; Ulf Risérus; Tommy Cederholm; Parveen Yaqoob; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dietary fat; Fatty acids; Serum fatty acid composition; Linoleic acid; Stearoyl coenzymeA desaturase; SCD-1; Inflammation; C-reactive protein; Oxidative stress; Lipid peroxidation; Isoprostanes; Prostaglandins; Obesity; Epidemiology; Dietary intervention; Metabolic syndrome; Nutrition; Näringslära; Epidemiology; Epidemiologi; Public health science; Folkhälsovetenskap; Immunology; Immunologi; Diabetology; Diabetologi; Cardiology; Kardiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Dietary fat quality influences the risk of type 2 diabetes and cardiovascular disease. A low-grade inflammation is suggested to contribute to the disease development, often accompanied by obesity. Whereas n-3 polyunsaturated fatty acids (PUFA) have been considered anti-inflammatory, n-6 PUFA have been proposed to act pro-inflammatory. LÄS MER

  4. 3. Growth hormone and PPARalpha in the regulation of genes involved in hepatic lipid metabolism

    Författare :Caroline Améen; Göteborgs universitet; []
    Nyckelord :Growth hormone; insulin; SREBP-1; lipogenic enzymes; microsomal triglyceride transfer protein; PPARalpha; LXRalpha; triglycerides; liver;

    Sammanfattning : Growth hormone (GH) plays a key role in the regulation of lipid and lipoprotein metabolism. Its sexually dimorphic secretory pattern regulates many sex-differentiated functions in the liver, such as triglyceride synthesis and VLDL secretion. LÄS MER

  5. 4. Determinants and clinical implications of circulating fatty acids in individuals with chronic kidney disease

    Författare :Xiaoyan Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :chronic kidney disease;

    Sammanfattning : Patients with chronic kidney disease (CKD) have a high risk of cardiovascular morbidity and mortality. Adding to traditional risk factors, e.g., Framingham risk factors, novel risk factors including inflammation, insulin resistance (IR) and metabolic syndrome (MetS) are being detected in patients with advanced CKD. LÄS MER

  7. 5. Novel lipid derivatives for health benefits : synthesis, analysis and effects in diet-induced obese mice

    Författare :Samanthi Madawala; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and thermogenesis are currently in focus to develop anti-obese food ingredients/nutraceuticals without side-effects. LÄS MER