Sökning: "Linoleic acid"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden Linoleic acid.

  1. 1. Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet

    Författare :Jonathan Cedernaes; Helgi B Schiöth; Robert Fredriksson; Anders Jacobsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adhesion GPCR; delta-5 desaturase; delta-6 desaturase; desaturase index; Diet-induced obesity; estimated desaturase activity; fatty acid composition; gas chromatography; gastrointestinal tract; G-protein coupled receptor; high-fat diet; intestine; linoleic acid; liver; mRNA expression; palmitoleic acid; plasma; phospholipids; proximodistal; RT-qPCR; solute carrier; SCD-1; SCD-16; SCD-18; stearoyl-CoA desaturase; subcutaneous adipose tissue; subsection; triacylglycerols.; Medical Genetics; Medicinsk genetik; Nutrition; Nutrition; Näringslära; Nutrition;

    Sammanfattning : The gastrointestinal tract (GIT) regulates nutrient uptake, secretes hormones and has a crucial gut flora and enteric nervous system. Of relevance for these functions are the G protein-coupled receptors (GPCRs) and the solute carriers (SLCs). LÄS MER

  2. 2. Conjugated linoleic acid and the metabolic syndrome : Clinical and metabolic studies with special reference to insulin resistance, oxidative stress and inflammation

    Författare :Ulf Risérus; Keith Frayn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Metabolic syndrome; dietary fatty acids; conjugated linoleic acid; insulin resistance; oxidative stress; inflammation; cardiovascular disease; dyslipidemia; abdominal obesity; type 2 diabetes; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Nutrition; näringslära;

    Sammanfattning : The aim of this thesis was to investigate the metabolic effects of conjugated linoleic acid (CLA) in middle-aged men with the metabolic syndrome, a high-risk group for type 2 diabetes. CLA is a group of fatty acid isomers with antiobesity and antidiabetogenic effects in animals, and CLA is therefore used as a supplement in humans. LÄS MER

  3. 3. Sources of Arachidonic Acid in Platelets, Bone, Marrow and Gastrointestinal Tract

    Författare :Li Zhou; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phospholipids; Megakaryocyte; Lysophosphatidylcholine; Lipoproteins; Linoleic acid; Intralipid; Interconversion; Gastrointestinal tract; Plasma free fatty acids; Fasting; Dietary fatty acids; Desaturase; Cholesterol; Chylomicron remnant; Chylomicron; Arachidonic acid; Bone marrow; Platelets; Protein S; Prothrombin; Triglycerides.; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : This study investigates pathways by which the eicosanoid precursor pools in the platelets, bone marrow and the gastrointestinal (GI) mucosa are acquired and regulated, and in this context some aspects on the interaction between triglyceride (TG)-rich lipoproteins and platelets. 1. LÄS MER

  4. 4. Milk Fat Intake and Conjugated Linoleic Acid (CLA) Supplementation : Dietary Markers and Associations to Clinical and Biochemical Characteristics

    Författare :Annika Smedman; Samar Basu; Bengt Vessby; Jan I Pedersen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nutrition; Pentadecanoic acid 15:0 ; milk products; milk fat; dietary marker; coronary heart disease; anthropometric variables; conjugated linoleic acid CLA ; lipid peroxidation; inflammation; F2 isoprostane; prostaglandin F2; human; Näringslära; Nutrition; Näringslära;

    Sammanfattning : In the present thesis dietary markers for intake of milk fat, associations between intake of milk fat and risk factors for coronary heart disease (CHD), and the effects of supplementation with conjugated linoleic acid (CLA) to healthy humans are investigated.The dietary fat quality is one of the main lifestyle factors affecting risk for CHD. LÄS MER

  5. 5. Dietary Fatty Acids, Body Composition and Ectopic Fat : Results from Overfeeding Studies in Humans

    Författare :Fredrik Rosqvist; Ulf Risérus; Tommy Cederholm; Ian Macdonald; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Linoleic acid; Palmitic acid; SFA; PUFA; Fatty acids; Body composition; Liver fat; Ectopic fat; Adipose tissue; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The aim of this thesis was to investigate the effects of dietary fatty acids on body composition and ectopic fat in humans, with emphasis on the role of the omega-6 polyunsaturated fatty acid (PUFA) linoleic acid (18:2n-6) and the saturated fatty acid (SFA) palmitic acid (16:0). The overall hypothesis was that linoleic acid would be beneficial compared with palmitic acid during overfeeding, as previously indicated in animals. LÄS MER