Sökning: "Per Aspenberg"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden Per Aspenberg.

  1. 1. Heterotopic Ossification : Clinical and Experimental Studies on Risk Factors, Etiology and Inhibition by Non-steroidal Anti-inflammatory Drugs

    Författare :Per-Erik Persson; Olle Nilsson; Per Aspenberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Heterotopic ossification; Hip prosthesis; NSAIDs; Prophylaxis; Prosthesis loosening; Reoperation; Animal model; Bone formation; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : In this thesis, occurrence of heterotopic ossification (HO) following total hip arthroplasty (THA) was studied. Preventive effects and complications with non-steroidal anti-inflammatory drugs (NSAIDs) were analyzed. Experimental investigations on bone formation were employed to gain insight to the mechanism of NSAIDs action on bone.(I). LÄS MER

  3. 2. Mechanisms of mechanically induced Osteoclastogenesis : in a novel in vitro model for bone implant loosening

    Författare :Cornelia Bratengeier; Anna Fahlgren; Per Aspenberg; Mikael Sigvardsson; Oran Kennedy; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Total joint arthroplasty is the primary intervention in the treatment of end-stage osteoarthritis. Despite the high success rate, in some patients, the replacement will fail during their lifetime requiring a revision of the implant. These revisions are strenuous for the patient and costly for health care. LÄS MER

  4. 3. Bisphosphonates and implants in the jaw bone

    Författare :Jahan Abtahi; Per Aspenberg; Agneta Marcusson; Lars Rasmusson; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Insertion of metal implants in bone is one of the commonest of all surgical procedures. The success of these operations is dependent on the fixation of the implants, which, in turn, depends on the strength of the bone that holds them. LÄS MER

  5. 4. Wnt signaling and metaphyseal bone healing

    Författare :Fredrik Agholme; Per Aspenberg; Lars Nordsletten; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : This thesis relates to some new aspects on the regulation of bone healing. In the last few years, Wnt-signaling has been shown to play a central role in bone biology. As well as being involved in bone maintenance and repair, Wnt-signaling has been presented as one of the key pathways through which bone responds to mechanical load. LÄS MER

  7. 5. Inflammation and tendon healing

    Författare :Parmis Blomgran; Per Aspenberg; Jan Ernerudh; Patrik Danielson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tendons heal through three different overlapping phases; the inflammatory, proliferative and remodeling phase. Many studies have investigated what factors influence healing of tendons. However, little was known about inflammation and the immune cells present during Achilles tendon healing by the time this thesis started. LÄS MER