Sökning: "POU Oct factors"

Hittade 3 avhandlingar innehållade orden POU Oct factors.

  1. 1. The Drosophila POU/Oct factors: multifaceted proteins

    Författare :Priya Gohel; Ylva Engström; Mariana Wolfner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; POU Oct factors; transcriptional regulation; innate immunity; developmental processes; mitotic spindles; chromosome segregation; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Dysregulation of physiological and cellular processes underlies various pathological conditions, including cancer and inflammatory disorders. Unraveling the molecular mechanisms driving these processes is crucial. LÄS MER

  3. 2. Role of POU/Oct transcription factors in Drosophila immunity

    Författare :Widad Dantoft; Ylva Engström; Anne Uv; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Drosophila; host-pathogen interaction; immune gene expression; immune signaling; NF-kB; microbiota; POU Oct transcription factors; protein degradation; stress response; transcriptional regulation; Molecular Biology; molekylärbiologi;

    Sammanfattning : In response to infection, Drosophila melanogaster relies on the ability to mount a robust and potent innate immune response, characterized by induction of cellular and humoral processes. While rapid immune induction is of utmost importance, it is equally important to restrict and repress immune gene expression, where and when it is not needed. LÄS MER

  4. 3. Expression of thioredoxin reductase 1 in mammalian cells with regulation by the core promoter and use of alternative splice variants

    Författare :Anna-Klara Rundlöf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Redox regulation; thioredoxin reductase; TXNRD1; selenoprotein; promoter; transcription; alternative splicing; expression;

    Sammanfattning : Reactive oxygen species are generated in cells as by-products of aerobic metabolism. To protect from damaging effects the cells possess several antioxidant systems and one of the most important is the thioredoxin system. LÄS MER