Sökning: "Nils Blüthgen"

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  1. 1. Into the Single-Verse : Subtle gene expression differences between virtually identical single cells are informative of gene regulation

    Författare :Marcel Tarbier; Marc Friedländer; Nils Blüthgen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Single-cell; quantitative; RNA biology; miRNA; functional genomics; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The ability to profile transcriptomes and proteomes in a high-throughput fashion in single cells has truly revolutionized functional genomics, and countless functional and regulatory insights have been based on these technologies. While major applications include the discovery of new cell types and the a posteriori sorting of cell populations, studies of gene expression noise and gene co-expression have made use of this inter-cellular heterogeneity in a genuine quantitative fashion. LÄS MER