Sökning: "Medulloblastoma"
Visar resultat 21 - 25 av 45 avhandlingar innehållade ordet Medulloblastoma.
21. Novel therapeutic targets in pediatric neural tumors
Sammanfattning : The embryonal tumors neuroblastoma and medulloblastoma are two of the most common and deadliest tumors in childhood. Both are heterogeneous tumors that arise in the peripheral and central nervous system, respectively. LÄS MER
22. Targeting dysfunctional developmental signaling cascades as a tool for tailored therapy in embryonal tumors
Sammanfattning : Neuroblastoma and medulloblastoma are embryonal malignant tumors of the central and peripheral nervous systems, respectively. The overall survival for both diagnoses is 60-75% despite intense multimodal therapy. This warrants the search for novel therapeutic approaches. LÄS MER
23. Molecular and epigenetic control of CNS tumour and progenitor cells
Sammanfattning : Despite advances in diagnosis and treatment, CNS tumours continue to result in high mortality and morbidity. Glioblastoma mutliforme (GBM), the most common primary brain tumour, is a recurrent tumour that despite advances in treatment, continues to demonstrate a median time of survival of 14.6 months. LÄS MER
24. The role of human cytomegalovirus infection in cancer
Sammanfattning : Cancer is a major cause of morbidity and mortality worldwide. It is thought that up to 20% of cancers are caused by infectious agents, and an oncogenic role of several viruses has been established for certain tumours. Increasing evidence implies that human cytomegalovirus (HCMV) infection is associated with a number of malignancies. LÄS MER
25. Notch signaling requiem : orchestral role of notch signaling in cancer and developmental disease
Sammanfattning : Notch signaling is an evolutionary conserved contact-dependent cell-cell communication pathway. This “contact” spans from hydra to fruit flies to human; orchestrating development, homeostasis and cancer, thus the Requiem, a song of life and death. LÄS MER
