Sökning: "Medulloblastoma"

Visar resultat 16 - 20 av 45 avhandlingar innehållade ordet Medulloblastoma.

1. 16. Elucidating the role of DNA damage and human cytomegalovirus in medulloblastoma and glioblastoma

   Författare :Jiri Bartek; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The most common primary malignant brain tumor in children is Medulloblastoma, while Glioblastoma is the most common in adults. Treatment for both include some combination of surgery, radiation therapy, and chemotherapy. LÄS MER

3. 17. Understanding and targeting the architecture in cancer : novel therapies in neuroblastoma and medulloblastoma

   Författare :Teodora Andonova; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cancer is the second leading cause of death worldwide after cardiovascular diseases. In Sweden, childhood cancer is the most common cause of death in children 1-14 years of age. Owing to advances in treatment and a better understanding of tumor biology, survival rates have increased to over 80% in most Western countries. LÄS MER

4. 18. Experimental combination therapy of brain cancer cell models

   Författare :Ana-Maria Marino; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Epigenetic alterations and aberrant expression of genes controlling epigenetic mechanisms have been identified in several cancers, including medulloblastoma and glioma, the most common primary brain tumors in children and adults, respectively. We have been investigating if combination therapy using histone deacetylase inhibitors (HDACi) and receptor tyrosine kinase inhibitors (RTKi) will enhance glioblastoma and medulloblastoma cell killing. LÄS MER

5. 19. Mechanisms acting on Hedgehog-GLI pathway and their therapeutic potential

   Författare :Ani Azatyan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Hedgehog signaling is crucial for diverse aspects of animal development, essential in regulating many cellular processes and is largely implicated in various forms of human cancer. However, many aspects of Hedgehog signaling are not completely understood. LÄS MER

7. 20. Omega-3 fatty acids in the treatment of childhood cancer

   Författare :Linda Ljungblad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Childhood cancer is the primary cause of deaths among Swedish children. Advances in treatment regimens have improved cure rate considerably in the latest decades. LÄS MER