Sökning: "Lora Deuitch Weidner"

Hittade 1 avhandling innehållade orden Lora Deuitch Weidner.

  1. 1. The role of ABC transporters and inflammation in drug-resistant epilepsy

    Författare :Lora Deuitch Weidner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis explores two pathologies thought to be related to drug resistance in epilepsy that may themselves be causally related: 1) overexpression of drug transporters in capillaries and 2) inflammation. With regard to the first hypothesis, overexpression of the ATP-binding cassette (ABC) transporters, P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), at the blood-brain barrier are thought to contribute to drug resistance in epilepsy. LÄS MER