Sökning: "Islet Microvasculature"

Hittade 2 avhandlingar innehållade orden Islet Microvasculature.

1. 1. The Microvasculature of Endogenous and Transplanted Pancreatic Islets : Blood Perfusion, Oxygenation and Islet Endocrine Function

   Författare :Richard Olsson; Per-Ola Carlsson; Leif Jansson; Arne Andersson; Thomas Linn; Uppsala universitet; []
   Nyckelord :Cell biology; diabetes mellitus; pancreatic islets; islet transplantation; vascular engraftment; islet microcirculation; oxygenation; blood flow; protein biosynthesis; Cellbiologi;

   Sammanfattning : Type 1 diabetes mellitus affects millions of people worldwide. Islet transplantation is a minimal invasive surgical procedure that restores euglycemia and halts the progression of diabetic complications. However, despite transplantation of islets from multiple donors most patients reverse to hyperglycemia within five years. LÄS MER

3. 2. Studies of the human pancreas to understand the pathologic events leading to type 1 diabetes

   Författare :Louise Granlund; Skog Oskar; Olle Korsgren; Marcus Lundberg; Per Andrén; Teresa Rodriguez-Calvo; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreas; Type 1 Diabetes; Islets of Langerhans; Exocrine tissue; Acinar cells; Islet Microvasculature; Endocrine cells; Extra-islet cells; Insulin; Glucagon; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Type 1 diabetes (T1D) is classically described as a disease emanating from beta-cell loss, and as such, the beta cells have been the main target of investigation. However, recent years have witnessed a shift in perspective, with T1D being increasingly recognized as a condition that affects the entire pancreas. LÄS MER