Sökning: "Flumazenil"

Visar resultat 6 - 10 av 10 avhandlingar innehållade ordet Flumazenil.

  1. 6. The Cross-Talk between GABA Signalling and Metabolic Hormones in the Brain and Pancreatic Islets

    Författare :Yang Jin; Bryndis Birnir; Vidar Gundersen; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : GABA is a well-known neurotransmitter that can be synthesized in the central nervous system (CNS) and, interestingly, also in pancreatic islets. Once released, GABA activates GABA-A channels tonically or transiently resulting in different physiological functions. LÄS MER

  3. 7. Disinhibitory and aggressive behavior in the rat. Neurohumoral mechanisms

    Författare :Anders I Svensson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Effective pharmacological treatment for impulsive aggression and dysfunctional impulsive behavior is needed. These behavioral disturbences in man and impulsive-like and aggressive behavior in animals may involve serotonin (5-HT), noradrenaline (NA), GABAA receptors and steroid hormones, e.g. testosterone. LÄS MER

  4. 8. Genotype-phenotype characterization of familial hyperkinetic movement disorders : emphasis on ataxia and brain calcifications

    Författare :Martin Paucar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Differential diagnosis of familial chorea encompasses Huntington’s disease along with a group of conditions referred to as Huntington’s disease-like (HDL). One such HDL is an inherited prion disorder (IPD) caused by pathological insertions of 8 additional OPRIS in the prion protein gene (PRNP). LÄS MER

  5. 9. Ion channels in drug discovery : focus on biological assays

    Författare :Kim Dekermendjian; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ion channels; GABAA receptor; sodium channels; TRPM8; drug discovery; high throughput screening assays; FLIPR; automated electrophysiology;

    Sammanfattning : Ion channels are well characterised drug targets. However, the techniques used to study ion channel pharmacology have not been particularly applicable to modern drug discovery. LÄS MER

  7. 10. Consequences of rape : injuries, posttraumatic stress and neuroendocrinological changes

    Författare :Anna Tiihonen Möller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Each year, approximately 3-4% of the Swedish female population experiences a sexual assault. Only a small percentage of these women will report the assault to the police, and even fewer will seek medical help. LÄS MER