Sökning: "Dosage"

Visar resultat 1 - 5 av 261 avhandlingar innehållade ordet Dosage.

1. 1. Towards Individualized Drug Dosage : General Methods and Case Studies

   Författare :Martin Fransson; Peter Fritzson; Lena Friberg; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; drug dosage; population pharmacokinetics; biochemical modelling; identifiability; parameter estimation; Bioinformatics; Bioinformatik;

   Sammanfattning : Progress in individualized drug treatment is of increasing importance, promising to avoid much human suffering and reducing medical treatment costs for society. The strategy is to maximize the therapeutic effects and minimize the negative side effects of a drug on individual or group basis. LÄS MER

3. 2. Pharmacokinetic dosing of factor VIII and factor IX in prophylactic treatment of haemophilia

   Författare :Maj Carlsson; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; Prophylaxis; Pharmacokinetics; Pharmaceutical service; Haemophilia B; Haemophilia A; Factor IX; Factor VIII; Drug distribution; Cost-effectiveness; Dosage; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : The aim of the thesis was to increase cost-effectiveness in prophylactic treatment of haemophilia. Prophylaxis is effective to prevent bleedings and arthropathy, but the high cost limits its use. First, a new distribution system for clotting factor concentrates was implemented in Sweden to improve availability and reduce risks and costs. LÄS MER

4. 3. Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation

   Författare :Ayman Al-Okshi; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CBCT; OPTIMISATION; DOSAGE;

   Sammanfattning : Inom odontologisk såväl som inom medicinsk radiologi sker en snabb utveckling av nya tekniker. Nya metoder för att kunna diagnosticera och följa sjukdomsförlopp över tid introduceras. Cone-Beam Computed Tomography (CBCT) är en sådan ny teknik, som introducerades inom odontologin under sent 1990-tal. LÄS MER

5. 4. Gadodiamide injection for Enhancement of MRI in the CNS. Applications, dose, field and time dependence

   Författare :Per Åkeson; Malmö Diagnostisk radiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical physics; Phantom study.; Comparative study; Human; Time dependence; Dosage; Enhancement; Gadolinium; MRI contrast media; Contrast media; Magnetic resonance imaging; Spine; Brain neoplasms; secondary; Brain; radiology; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

   Sammanfattning : Aims of the study The aims of this study using Gadodiamide injection were to investigate: · Whether Gadodiamide injection was comparable to Gd-DTPA for the enhancement of CNS lesions. · The contrast effect at different field strengths. · The effective time-window for the enhancement of blood-brain barrier damage. LÄS MER

7. 5. The Evolution of Sex Chromosomes and Dosage Compensation in Structurally Dynamic Butterfly Genomes

   Författare :Lars Höök; Niclas Backström; Elina Immonen; Beatriz Vicoso; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome evolution; Dosage compensation; Sex-biased gene expression; Faster-Z; Lepidoptera; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : Dimorphic sex chromosomes have evolved independently throughout evolution from initially homologous autosomes. Recombination suppression between the sex chromosomes causes one sex chromosome to degenerate, which will influence evolution of sex-linked genes. LÄS MER