Sökning: "Cyclooxygenases COXs"

Hittade 2 avhandlingar innehållade orden Cyclooxygenases COXs.

1. 1. Tumor progression in the ovary and colon. The interaction of Wnt-signaling, transcription and formation of prostaglandins

   Författare :Katarina Rask; Göteborgs universitet; []
   Nyckelord :CCAAT Enhancer Binding Proteins C EBPs ; Wingless Wnt Wnt signaling pathway; Cyclooxygenases COXs ; colorectal cancer CRC ; epithelial ovarian cancer EOC ;

   Sammanfattning : Alterations in cell-cell adhesion, intracellular signaling and transcriptional regulation are common events during transformation of cells to the malignant phenotype. Different cellular defense mechanisms, e.g. inflammatory responses, mediated by prostaglandins, have also been associated with tumor development. LÄS MER

3. 2. Prostaglandin modulation of airway hyperresponsiveness and inflammation in murine models of asthma

   Författare :Linda Swedin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterised by chronic inflammation, reversible bronchoconstriction and airway hyperresponsiveness (AHR). The cyclooxygenases (COXs) are key enzymes in the biosynthesis of prostaglandins, which have diverse physiological and pathological functions, and are also important modulators of inflammatory responses in the lung. LÄS MER