Sökning: "Circulating tumor cells CTCs"

Hittade 4 avhandlingar innehållade orden Circulating tumor cells CTCs.

  1. 1. Isolation of Circulating Tumor Cells with Acoustophoresis : Towards a biomarker assay for prostate cancer

    Författare :Eva Undvall; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Biomarkers; Cell separation; Circulating tumor cells CTCs ; Elastomeric particles; Microfluidics; Negative selection; Prostate Cancer;

    Sammanfattning : Microfluidics has emerged as an essential approach in the development of novel technological platforms to detect and isolate rare circulating tumor cells (CTCs) in the blood of cancer patients. Micro-scaled fluidic systems offer means to precisely control fluid flow. LÄS MER

  3. 2. The application of microfluidic devices and multifunctional fibers in cancer diagnostics

    Författare :Tharagan Kumar; Aman Russom; Fredrik Laurell; Gustaf Mårtensson; Johan Kreuger; KTH; []
    Nyckelord :Circulating tumor cells; microfluidics; point of care; inertial microfluidics; elasto inertial microfluidics; nano-cellulose; layer-by-layer; optical fiber; microflow cytometer.; Bioteknologi; Biotechnology;

    Sammanfattning : Efficient separation and detection of rare cells in a mixed population is important in many biomedical applications. For instance, isolating and detecting circulating tumor cells (CTCs) from whole blood samples could allow for early cancer diagnosis and prognosis during treatment. LÄS MER

  4. 3. Receptor tyrosine kinases and circulating tumor cells as new prognostic biomarkers in breast cancer with special focus on TNBC

    Författare :Sara Jansson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bröstcancer;

    Sammanfattning : About 8000 Swedish women are diagnosed with breast cancer each year, and around 1500 die from the disease. Triple-negative breast cancer (TNBC) constitutes 7-14% of all breast cancer and is characterized by an aggressive phenotype with poor prognosis and no targeted therapy available. LÄS MER

  5. 4. Pharmacometric Evaluation of Biomarkers to Improve Treatment in Oncology

    Författare :Ida Netterberg; Lena Friberg; Mats Karlsson; Elisabet I. Nielsen; Henrik Lindman; Amit Roy; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; Biomarkers; Oncology; Population PKPD Modeling; NONMEM; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Cancer is a family of many different diseases with substantial heterogeneity also within the same cancer type. In the era of personalized medicine, it is desirable to identify an early response to treatment (i.e., a biomarker) that can predict the long-term outcome with respect to both safety and efficacy. LÄS MER