Sökning: "CTC"

Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet CTC.

  1. 1. Ultrasensitive Molecular Monitoring of Breast Cancer and Acute Myeloid Leukemia

    Författare :Yilun Chen; Translational Oncogenomics; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; AML; PTEN; PI3K; Liquid biopsy; Sequencing; cfDNA; ctDNA; Structural variants; Mammography; CTC; Mutation detection; IBSAFE; MRD;

    Sammanfattning : Cancer is the common name to a group of biologically diverse malignant neoplastic diseases. Approximately 18 million people are diagnosed with cancer annually and 8.8 million patients die from it. Tumorigenesis and progression of cancer are driven by alterations in the cancer cell genome. LÄS MER

  3. 2. Molecular Markers and Hypoxia in Renal Cell Carcinoma

    Författare :Roger de Alwis; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney cancer; CTC; RCC; Hypoxia; SEMA5B; Prognostic markers;

    Sammanfattning : Renal cell carcinomas (RCCs) are a group of tumours that arise from the nephron within the kidney. They are characterised by an indolent growth pattern and do not display overt clinical symptoms in patients with early to locally advanced tumours. LÄS MER

  4. 3. Label-free processing of stem cell preparations by acoustophoresis

    Författare :Franziska Olm; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acoustophoresis; label-free cell separation; ultrasound; microfluidics; stem cell processing; CTC separation;

    Sammanfattning : The first bone marrow transplant in a human was performed in 1959, providing evidence that cells can be used for transplantation and treatment, revealing that healing capacities lie within the human body that ought to be understood. Since then hematopoietic stem cell transplantation has developed as a standard treatment for many cancers besides other malignancies. LÄS MER

  5. 4. Receptor tyrosine kinases and circulating tumor cells as new prognostic biomarkers in breast cancer with special focus on TNBC

    Författare :Sara Jansson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bröstcancer;

    Sammanfattning : About 8000 Swedish women are diagnosed with breast cancer each year, and around 1500 die from the disease. Triple-negative breast cancer (TNBC) constitutes 7-14% of all breast cancer and is characterized by an aggressive phenotype with poor prognosis and no targeted therapy available. LÄS MER

  7. 5. BRICHOS - a Novel Anti-Amyloid Chaperone : studies on pro-surfactant protein C

    Författare :Hanna Willander; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Lung surfactant protein C (SP-C) is a 35-residue, transmembrane (TM) peptide that is extremely hydrophobic and lacks known homologous proteins. Due to a high content in Val residues in the α-helical TM part, SP-C can spontaneously convert into β-sheet aggregates. LÄS MER