Sökning: "Anne-Lise Børresen-Dale"
Hittade 2 avhandlingar innehållade orden Anne-Lise Børresen-Dale.
1. Genetic Alterations in Early Onset Breast Cancer
Sammanfattning : Cancer is in essence a genetic disease, brought about by an accumulation of alterations in genes that encode proteins responsible for the control of cell growth, cell death and the maintenance of genomic integrity. Recent years have seen the unravelling of numerous genes that are targeted in carcinogenesis. LÄS MER
2. Somatic Mutations in Breast Cancer Genomes : Discovery and Validation of Breast Cancer Genes
Sammanfattning : Breast cancer is the most common cancer in women worldwide. However, the genetic alterations that lead to breast cancer are not fully understood. This thesis aims to identify novel genes of potential mechanistic, diagnostic or therapeutic interest in breast cancers by mutational analysis and whole-genome sequencing. LÄS MER