Sökning: "Anja Henningsson"

Hittade 1 avhandling innehållade orden Anja Henningsson.

1. 1. Mechanism-Based Pharmacokinetic and Pharmacodynamic Modelling of Paclitaxel

   Författare :Anja Henningsson; Mats O. Karlsson; Lena Friberg; Iñaki F. Trocóniz; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Mechanism-based; Modelling; Myelosuppression; Paclitaxel; Cremophor EL; NONMEM; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

   Sammanfattning : Paclitaxel (Taxol®) is now widely used against breast, ovarian and non-small-cell lung cancer. Anticancer agents generally have narrow therapeutic indices, often with myelosuppression (mainly neutropenia) as dose-limiting side effect. LÄS MER