Sökning: "Richeng Jiang"

Hittade 1 avhandling innehållade orden Richeng Jiang.

1. 1. Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease

   Författare :Richeng Jiang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Alzheimer’s disease (AD), the most common neurodegenerative disease, is characterized by two pathological hallmarks: extracellular amyloid-beta peptide (Aβ) plaque depositions and neurofibrillary tangles (NFTs) composed of intracellular hyperphosphorylated tau aggregations. A cellular degradation system, autophagy is additionally dysfunctional in AD and plays a key role in Aβ and tau metabolisms. LÄS MER