Sökning: "thyroid"

Visar resultat 6 - 10 av 272 avhandlingar innehållade ordet thyroid.

  1. 6. Regulation of apoptosis in the thyroid epithelium

    Författare :Abeba Demelash; Göteborgs universitet; []
    Nyckelord :Thyroid; Apoptosis; Caspase; Calpain; Hydrogen peroxide; TGF-beta; Staurosporine; Selenium; Cytochrome c;

    Sammanfattning : Apoptosis or programmed cell death allows the multicellular organism to remove cells that are in excess or potentially dangerous. Apoptosis has to be strictly controlled, yet inappropriately activated or suppressed apoptototic may contribute to a variety of diseases, including cancer, autoimmune disorders and neurodegenerative conditions. LÄS MER

  3. 7. In vitro radiobiological effects of 131I on thyroid cells: towards a mechanistic understanding of thyroid stunning

    Författare :Nirmal Bhogal; Göteborgs universitet; []
    Nyckelord :thyroid; radioiodide; stunning; 131I; stress response; DNA damage; Chk2; H2AX; micronuclei; cell cycle;

    Sammanfattning : .... LÄS MER

  4. 8. Hypothyroidism and Pregnancy

    Författare :Michaela Granfors; Anna-Karin Wikström; Inger Sundström-Poromaa; Helena Åkerud; Ulla Feldt-Rasmussen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phosphodiesterase 8B; recurrent miscarriage; single nucleotide polymorphism; thyroid; guidelines; hypothyroidism; pregnancy; survey; thyroid testing; screening; iodine; iodine deficiency; median urinary iodine concentration; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Hypothyroidism is a common endocrine disorder affecting women of reproductive age. On a global level, iodine deficiency is still the most common cause of hypothyroidism. Also genetic variations, in particular SNP rs4704397 in the PDE8B gene, are responsible for a significant proportion of TSH variations. LÄS MER

  5. 9. Regulation of E-cadherin mediated adhesion in thyroid epithelial cells

    Författare :Fredrik Larsson; Göteborgs universitet; []
    Nyckelord :thyroid; adherens junction; E-cadherin; thyrotropin; cAMP; PKA; Epac; IQGAP;

    Sammanfattning : Cell adhesion is one of multicellular organisms most fundamental features. Cells connect to each other by transmembrane proteins arranged in junction complexes. LÄS MER

  7. 10. Classical cadherins and the thyroid. Studies on organ development and epithelial differentiation

    Författare :Mats Grände; Göteborgs universitet; []
    Nyckelord :Thyroid; cadherin; TGF-; EGF; MEK; development; EMT;

    Sammanfattning : The cadherins are key regulators of tissue patterning and organ formation. E-cadherin is important for cell-cell adhesion and promotes epithelial morphogenesis and maintenance of the epithelial phenotype. LÄS MER