Sökning: "synovial lining cells"

Hittade 4 avhandlingar innehållade orden synovial lining cells.

  1. 1. Studies of the synovial membrane in chronic rheumatic joint disease

    Författare :Erik af Klint; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: The synovial membrane (SM) outlines the inner cavity of synovial joints except for cartilage surfaces. The SM is the target organ of immune-mediated responses in chronic arthritis, including rheumatoid arthritis (RA). RA is a common joint disease (prevalence of 0.5-1. LÄS MER

  3. 2. Opioid ligands and receptors of the joint

    Författare :Jonas Bergström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Opioid peptides; enkephalin; opioid receptors; joint; primary afferents; synovial lining cells; vascular smooth muscle; arthritis; osteoarthrosis; immunohistochemistry; radioimmunoassay; RTPCR; binding assay;

    Sammanfattning : The aim was to explore the occurrence of an opioid system in joints. Thus, joint tissues from rats with and without arthritis and also from patients with knee osteoarthrosis were investigated by EM, immunohistochemistry, RIA, HPLC, receptor binding assay and RT-PCR. LÄS MER

  4. 3. Studies on novel immunosuppressive agents in experimental arthritis

    Författare :Thi Ngoc Dzung Dang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Artocarpus Tonkinensis; Collagen-induced arthritis; apoptosis; immunosuppression;

    Sammanfattning : Rheumatoid Arthritis (RA) is a chronic inflammatory disease of the joints. The hallmark of RA is persisting inflammation in diarthrodial joints with infiltration of leukocytes, thickening of the synovial lining layer and synovial pannus formation. LÄS MER

  5. 4. Cytokines and cytokine-directed intervention in experimental arthritis

    Författare :Karin Palmblad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :pro-inflammatory cytokines; collagen-induced arthritis; CNI-1493; HMG-1;

    Sammanfattning : Rheumatoid arthritis (RA) is a common chronic autoimmune and inflammatory disease. Although the etiology of RA remains unknown, a general understanding of the pathogenesis is steadily increasing. The macrophage products tumor necrosis factor (TNF) and interleukin 1 (IL-1) are recognized as pivotal mediators in the arthritic process. LÄS MER