Sökning: "serum glycoproteins"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden serum glycoproteins.

  1. 1. FROM SERUM TO TISSUE: GALECTIN-BINDING GLYCOFORMS OF SERUM GLYCOPROTEINS AS FUNCTIONAL BIOMARKERS

    Författare :Michael Carlsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Galectin; glycoproteins; intracellular sorting; biomarkers;

    Sammanfattning : Galectins are small soluble proteins defined by a conserved sequence motif that forms a defining β-galactoside binding site shared among galectins; adjacent binding sites give each galectin a unique fine specificity for a specific subset of galactose containing glycans. A wealth of data now suggests important roles of galectins in both cancer and inflammation. LÄS MER

  3. 2. Galectin binding proteins in serum and bronchoalveolar lavage -in healthy and pathological conditions

    Författare :Cecilia Cederfur; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; glycoprotein; asthma; bronchoalveolar lavage; galectin binding protein; galectin ligand; galectin; serum;

    Sammanfattning : Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. LÄS MER

  4. 3. Reading a glycocode - mechanism and function of galectin-glycan interactions

    Författare :Emma Salomonsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin; specificity; affinity; multivalency; fluorescence anisotropy; glycan array; serum glycoproteins; anginex;

    Sammanfattning : There is an intensive interest in characterising the structure and function of galectins, which is not surprising given their many important cellular functions and strong implications in human disease. Understanding the mechanisms involved in galectin functions will help to find selective and novel strategies for disease treatment and diagnosis. LÄS MER

  5. 4. The role of glycoproteins in glomerular pathophysiology

    Författare :Alina Khramova; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteoglycans; Extracellular matrix; IgA nephropathy; Diabetic kidney disease;

    Sammanfattning : Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no specific treatments available and mechanisms behind the onset and progression of CKD are still not fully investigated. LÄS MER

  7. 5. Viral proteins as serological antigens - Development and clinical applications

    Författare :Linn Persson Berg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Serology; ELISA; IgG; Varicella-zoster virus; Epstein-Barr virus; Measles virus; Viral glycoproteins; Multiple sclerosis;

    Sammanfattning : Serological methods are based on the detection of antibodies and antigens in mainly serum but also in other body fluids such as cerebrospinal fluid (CSF). Conventional whole virus antigens are widely used in viral serological assays. LÄS MER