Sökning: "prediction of solubility"

Visar resultat 11 - 15 av 25 avhandlingar innehållade orden prediction of solubility.

1. 11. In vitro-solubility and supersaturation behavior of supersaturating drug delivery systems

   Författare :Amani AlHayali; Sitaram P. Velaga; Sandra Klein; Luleå tekniska universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Health Science; Hälsovetenskap;

   Sammanfattning : The development of new pharmaceutical products has been challenged by the growing number of poorly water-soluble drugs, which often lead to suboptimal bioavailability. Various approaches, such as the use of amor-phous solid dispersions and cocrystals, have been used to improve the solu-bility, and subsequent bioavailability, of these drug molecules. LÄS MER

3. 12. Modelling and prediction of drug transport processes with experimental and calculated molecular properties : A multivariate approach

   Författare :Thomas Österberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Sammanfattning : Less than 2% of the lead compounds generated by the pharmaceutical industry enter the exploratory drug-development phase, from which point they stand only a 10% chance of becoming a commercial medicine. A large proportion of the compounds fail due to poor biopharmaceutical properties, such as permeability and solubility. LÄS MER

4. 13. Comparison of experimentally and theoretically determined oxidation and photochemical transformation rates of some organohalogens to promote prediction of persistence

   Författare :Patricia Moreira Bastos; Åke Bergman; Leif Kronberg; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oxidation; Persistence; Photolysis; QSPR; BFRs; PBDEs; OH-PBDEs; Chemistry; Kemi; miljökemi; Environmental Chemistry;

   Sammanfattning : The diversity of choices we have to make everyday influence our environment and ourselves in more ways than most of us realise. Anthropogenic substances, such as flame retardants, date back as early as 450 BC when the Egyptians used alum to reduce flammability. LÄS MER

5. 14. Alloy Design and Optimization of Mechanical Properties of High-Entropy Alloys

   Författare :Saad Ahmed Sheikh; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ductility; topologically closed-pack TCP and geometrically closed-pack GCP phase; alloy design; mechanical properties; High-entropy alloys; refractory high-entropy alloys; valence electron concentration;

   Sammanfattning : High-entropy alloys (HEAs) are described as alloys containing multi-principal elements in equal or close to equal atomic percentage. HEAs are considered as potential structural materials for high-temperature applications; where alloy design and optimization of mechanical properties is extremely critical. LÄS MER

7. 15. Solubility of hydrogen in slags and its impact on ladle refining

   Författare :Jenny Brandberg; Du Sichen; Mia Almcrantz; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Other materials science; Övrig teknisk materialvetenskap;

   Sammanfattning : The aim of the present work was to clarify the mechanisms of hydrogen removal during vacuum degassing. The main reason for this was because the primary source of hydrogen pick-up in steel-making is the moisture in the furnace atmosphere and the raw material charged into the ladle furnace. LÄS MER