Sökning: "polycystic ovary syndrome PCOS"

Visar resultat 16 - 20 av 36 avhandlingar innehållade orden polycystic ovary syndrome PCOS.

  1. 16. Polycystic ovary syndrome (PCOS) : role of androgens and obesity on placental function and fetal development

    Författare :Romina Fornes; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting women in childbearing age with a prevalence of up to 17.8%. The syndrome is characterized by hyperandrogenism, irregular cycles and polycystic ovaries. The etiology of PCOS is unclear, but it is thought to be multifactorial. LÄS MER

  2. 17. Polycystic ovary syndrome : a study of adipocyte lipolysis in relation to endocrine and metabolic status

    Författare :Ingvar Ek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adipocyte; beta-adrenoceptors; FFA; hyperandrogenism; HSL; insulin resistance; lipolysis; PCOS; PKA;

    Sammanfattning : The aim of the present thesis was to obtain insight into possible regulatory effects of androgens on the regulation of lipolysis in subcutaneous as well as visceral adipose tissue in women with the polycystic ovary syndrome (PCOS). In non-obese women with PCOS, adrenergic lipolysis was investigated in both subcutaneous abdominal and visceral adipose tissue and several, novel disturbances were found. LÄS MER

  3. 18. Developmental origins of polycystic ovary syndrome : role of early adverse life events on adult health

    Författare :Maria Manti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The research focus of this thesis is polycystic ovary syndrome (PCOS), the most common endocrine disorder among women of reproductive age, associated with reproductive, cardio-metabolic, and mental health complications. Despite the high prevalence, little is known about the etiology of the syndrome. LÄS MER

  4. 19. Mass Spectrometric Applications for Diagnosing Metabolic and Endocrine Diseases

    Författare :Mark M. Kushnir; Jonas Bergquist; Alan L Rockwood; David Herold; Uppsala universitet; []
    Nyckelord :Analytical chemistry; biomarker; liquid chromatography; tandem mass spectrometry; LC-MS MS; sample preparation; isomers; steroid hormones; congenital adrenal hyperplasia; polycystic ovary syndrome; Analytisk kemi;

    Sammanfattning : Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnosing diseases. This thesis describes development and validation of liquid chromatography tandem mass spectrometry (LC-MS/MS) based tests for diagnosing a diverse group of endocrine and metabolic diseases. LÄS MER

  5. 20. Acupuncture in reproductive medicine. Applications in human assisted reproduction and aspects of clinical and experimental neuroendocrinology

    Författare :Elisabet Stener-Victorin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electro-acupuncture; blood flow impedance; circulation; uterine artery; in-vitro fertilization; oocyte aspiration; polycystic ovary syndrome; experimentally induced PCO; anovulation; gonadotropins; steroids; neuropeptides; b-endorphin; nerve growth factor; corticotropin-releasing factor.;

    Sammanfattning : The use of acupuncture in the area of reproductive medicine is relatively new, and it has been rather poorly investigated in the past. When muscle afferents are stimulated by acupuncture in somatic segments related to the innervation of the ovaries and the uterus, functional changes occur in the neural substrate that may influence reproductive function and result in peripheral, segmental and central effects. LÄS MER