Sökning: "ovarian carcinoma"

Visar resultat 36 - 40 av 44 avhandlingar innehållade orden ovarian carcinoma.

  1. 36. Heparan sulfate dependent cell signaling and associated pathophysiology : Implications in tumorigenesis and embryogenesis

    Författare :Tahira Batool; Jin-Ping Li; Aristidis Moustakas; Liliana Schaefer; Ingvar Ferby; Michael Welsh; Anders Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Glucuronyl-C5 epimerase; Heparan Sulfate; Heparin; Lung Cancer; Cancer cell Singling; TGF-Beta; BMP; VEGF; Notch Signaling; Tumor growth; Metastasis; embryonic development; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Heparan sulfate proteoglycans (HSPGs) consist of a protein core to which several linear, negatively charged heparan sulfate (HS) chains are covalently attached. HSPGs are expressed on the cell surface and in the extra-cellular matrix (ECM) where they have diverse biological functions, for example co-receptor functions. LÄS MER

  3. 37. Population-based family studies : genetic contribution to cancer development and survival?

    Författare :Linda Sofie Lindström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer affects essentially everyone, directly or indirectly. The aim of this thesis was to study the genetic and environmental factors in cancer development and survival. LÄS MER

  4. 38. On the role of notch, numb and numblike in development and cancer

    Författare :Lining Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of mutlicellualr organisms relies on a highly conserved signaling network, of which one of the key components is the Notch signaling pathway. The core Notch signaling pathway consists of receptors, ligands and an intracellular mediator. LÄS MER

  5. 39. Modulation of natural killer cell and T-cell functions by CD94/NKG2A receptors

    Författare :Cristina Teixeira de Matos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; Dendritic cells; Inhibitory receptors; Cytokines; C1394 NKG2A; HLA-E; Inflammation; Chronic arthritis; Tumor cells.;

    Sammanfattning : Natural Killer (NK) cells constitute a subset of lymphocytes capable of cytokine production and/or cellular cytotoxicity. Although NK cells can be activated experimentally by a multitude of agents, the in vivo mechanisms of activation and regulation are not fully elucidated. LÄS MER

  7. 40. Hereditary factors in endometrial cancer

    Författare :Gerasimos Tzortzatos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Endometrial carcinoma (EC) is the most common gynecological malignancy in Sweden and accounts for about 6 % of all female malignancies. The risk of EC increases with age and the majority of cases are diagnosed between age 50 and 60. Ninety percent of cases occur in women older than age 50. LÄS MER