Sökning: "oral vaccination"

Visar resultat 6 - 10 av 24 avhandlingar innehållade orden oral vaccination.

  1. 6. Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses

    Författare :Tanvir Ahmed; Göteborgs universitet; []
    Nyckelord :Vibrio cholerae; ETEC; oral vaccine; CS6; CFA I; Lewis blood group; zinc; breast feeding; T cell; B cell;

    Sammanfattning : Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses Abstract Vibrio cholerae O1 and enterotoxigenic Escherichia coli (ETEC) together account for the majority of bacterial causes of acute dehydrating diarrhea in children in Bangladesh. Vaccines should be considered as an important public health tool for prevention of these diarrheal diseases. LÄS MER

  2. 7. Mucosal Vaccination Using Polyacryl Starch Microparticles as Adjuvant with Salmonella enteritidis as a Model Pathogen

    Författare :Lena Strindelius; Ingvar Sjöholm; Mary Jo Wick; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; mucosal vaccination; polyacryl starch microparticles; salmonella enteritidis; flagellin; fimbriae; rCTB; LPS; Ussing chamber; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Polyacryl starch microparticles have been developed as a new mucosal vaccine adjuvant intended for use in oral vaccination. The main objectives of this thesis were to evaluate the efficacy of these polyacryl starch microparticles and to study their uptake through mucosal tissues. LÄS MER

  3. 8. Genetic modification of cholera toxin B subunit for mucosal anti-infectious or anti-pathologic vaccination

    Författare :Hamid Sadeghi; Göteborgs universitet; []
    Nyckelord :Genetic fusion protein; cholera toxin B subunit; insulin; GST; Oral tolerance;

    Sammanfattning : The development of mucosal vaccines requires antigen delivery systems that can efficiently help to present vaccine antigens to the mucosal immune system. En efficient and well known antigen carrier/delivery system is the B subunit of cholera toxin (CTB). LÄS MER

  4. 9. Pneumococcal vaccination in inflammatory rheumatic disease. Antibody response and protection against infections

    Författare :Johanna Nagel; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vaccination; pneumococci; inflammatory rheumatic disease;

    Sammanfattning : AbstractObjectives: Patients with inflammatory rheumatic diseases (IRDs) have higher risk of serious infections than healthy individuals due to their illness, comorbidities and treatments. Streptococcus pneumoniae is responsible for 30-50% of community aquired pneumonia in Europe. LÄS MER

  5. 10. Immune responses related to protection against rotavirus after natural infection and vaccination

    Författare :Kari Johansen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotavirus is the most important cause of severe gastroenteritis in children under five years of age and is estimated to be responsible for one-third of all diarrhea-associated hospitalizations and 600,000 deaths/ year worldwide. 1500-1700 rotavirus-associated hospitalizations of children are estimated to occur annually in Sweden (3. LÄS MER