Sökning: "monophasic action potential"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden monophasic action potential.

  1. 1. Global sequence and dispersion of ventricular repolarization: In vivo validation of non-invasive parameters using monophasic action potential mapping technique

    Författare :Yunlong Xia; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; dispersion; electroanatomical mapping; T wave; epicardial pacing; Ventricular repolarization; monophasic action potential;

    Sammanfattning : The purposes are to validate the noninvasive parameters, QT interval, QT dispersion, Tpeak-Tend interval, and the activation recovery time (ART) for estimation of global dispersion of ventricular repolarization (DVR), and to investigate the changes of repolarization sequence and DVR by altered ventricular pacing sites. The material consisted of 12 patients (Study I) and two series healthy pigs with 10 in each (Studies II and III; Studies IV and V). LÄS MER

  2. 2. SEQUENCE AND DISPERSION OF VENTRICULAR REPOLARIZATION ON THE ENDOCARDIUM AND EPICARDIUM Studies using the monophasic action potential mapping technique in humans and pigs

    Författare :Ole Kongstad Rasmussen; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; ventricle; epicardium; endocardium; Monophasic action potential mapping Repolarization sequence; Global dispersion;

    Sammanfattning : Materials and Methods: Monophasic action potential (MAP) were recorded, using the CARTO mapping system and NaviStar catheters, during sinus rhythm from the endocardium at 43 ± 15 LV or RV sites in 8 patients, at 61 ± 18 LV and/or RV sites in 10 pigs and during atrial pacing from the endo- and epicardium at 211 ± 54 LV and RV sites in additional 10 pigs. Local activation time (AT), MAP duration (MAPd) and end-of-repolarization time (EOR) were calculated at each site and 3-dimensional maps of AT, EOR and MAP duration on the endo- and epicardium were obtained. LÄS MER

  3. 3. Sequence and dispersion of repolarization of the right atrium: Implications of repolarization disturbance in atrial fibrillation

    Författare :Zhen Li; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; electroanatomical mapping; monophasic action potential; atrial fibrillation; repolarization; dispersion;

    Sammanfattning : To explore the global sequence and dispersion of repolarization of the right atrium, monophasic action potentials (MAPs) were sequentially recorded from the right atrium using an electroanatomical mapping (CARTO) system in 10 healthy pigs and in 10 patients with (n=6) and without (n=4) paroxysmal atrial fibrillation (PAF) during sinus rhythm, or using two MAP recording catheters in 30 patients with or without PAF (n=15 each) during sinus rhythm, pacing, and programmed stimulation. The dispersion of activation time (AT), repolarization time (RT) and MAP duration (MAPd) were analyzed. LÄS MER

  4. 4. The Physical Axon : Modeling, Simulation and Electrode Evaluation

    Författare :Malcolm Latorre; Karin Wårdell; Göran Salerud; Ulrich Hofmann; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Electrodes are used in medicine for detection of biological signals and for stimulating tissue, e.g. in deep brain stimulation (DBS). For both applications, an understanding of the functioning of the electrode, and its interface and interaction with the target tissue involved is necessary. LÄS MER

  5. 5. Immunogenetics and treatment of experimental autoimmune encephalomyelitis

    Författare :Robert Weissert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple sclerosis; experimental autoimmune encephalomyelitis; major histocompatibility complex; myelin; myelin oligodendrocyte glycoprotein; T cell receptor;

    Sammanfattning : Experimental autoimmune encephalomyelities (EAE) is a model of multiple sclerosis (MS). This experimental central nervous system (CNS) disease can be induced in rats by immunization with components of the CNS myelin sheath. LÄS MER