Sökning: "hormone treatment"

Visar resultat 1 - 5 av 511 avhandlingar innehållade orden hormone treatment.

  1. 1. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment

    Författare :Elena Lundberg; Berit Kriström; Kerstin Albertsson-Wikland; Roland Pfäffle; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gain in height; puberty; IGHD; non-GHD; IGF-I; bioavailability;

    Sammanfattning : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. LÄS MER

  3. 2. Hormone replacement therapy : benefits and adverse effects

    Författare :Inga-Stina Ödmark; Mats Hammar; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone replacement therapy HRT ; bleeding pattern; progestogen; wellbeing; side effects; lipoprotein a ; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background: Numerous studies have shown that estrogen replacement therapy (ERT) is an effective treatment for vasomotor symptoms, insomnia and vaginal dryness. Beneficial effects have also been shown on lipid patterns and on the incidence of osteoporotic fractures. LÄS MER

  4. 3. Metabolic responsiveness to growth hormone in children

    Författare :Ralph Decker; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Individualized treatment; Growth hormone; Hormonal responsiveness; Metabolic outcome; Prediction model; Body composition; Insulin sensitivity; Leptin; Proteomics SELDI; Apolipoproteins; Thresholds of growth hormone effects; Protein patterns;

    Sammanfattning : Metabolic effects of growth hormone (GH) therapy in short children have not been clearly established owing to the previous lack of controlled trials studying the metabolic outcome in response to different GH doses despite the known effects of GH on insulin sensitivity, lipid profile, and body composition. It has previously been shown that individualized GH doses during catch-up growth significantly reduce the proportion of unexpectedly good and poor responders around a predefined individual growth target in short prepubertal children. LÄS MER

  5. 4. Cardiovascular effects of growth hormone, IGF-I and growth hormone secretagogues

    Författare :Åsa Tivesten; Göteborgs universitet; []
    Nyckelord :cardiovascular system; growth hormone; insulin-like growth factor-I; growth hormone secretagogues; echocardiography.;

    Sammanfattning : Growth hormone (GH) may exert direct growth-promoting and metabolic actions on target tissues, but most of its effects are mediated by circulating (endocrine) or local (auto-/paracrine) insulin-like growth factor-I (IGF-I). The GH/IGF-I system has an important role during cardiac development and for maintaining the structure and function of the heart. LÄS MER

  7. 5. Growth Hormone and Gender. Studies in Healthy Adults and in Patients with Growth Hormone Disorders

    Författare :Britt Edén Engström; Uppsala universitet; []
    Nyckelord :Medical sciences; Growth hormone; gender; ambulation; oral contraceptives; epinephrine; GH treatment; age; E2-implant; IGF-I; octreotide; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : The use of a new, more sensitive immunoassay for growth hormone (GH) revealed that the serum levels in men were lower than expected in sera drawn ambulatory in the morning after an overnight fast and that the gender difference was more than 10 times greater than reported. These observations led to a more thorough study on the impact of gender and sex steroids on the levels of GH and other hormones in ambulatory morning samples and over a 24-hour period. LÄS MER