Sökning: "duodenal ulcer"

Visar resultat 21 - 25 av 35 avhandlingar innehållade orden duodenal ulcer.

  1. 21. Characterization of antibodies against Helicobacter pylori

    Författare :Jun Cao; Göran Nilsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : H. pylori is associated with the development of peptic ulcer, gastritis, and gastric cancer. Eradication of H. pylori by antibiotic treatment gives a healing of peptic ulcer and gastritis. LÄS MER

  3. 22. Neutrophil recruitment in H. pylori induced inflammation: characterization of regulatory factors

    Författare :Mikael Innocenti; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; endothelial cells; neutrophils; monocytes; transendothelial; migration; chemokines; cytokines; adhesion molecules inflammation; LPS; CagPAI; VacA;

    Sammanfattning : Helicobacter pylori, a bacterium colonizing the human gastric mucosa, is strongly associatedwith the development of gastric and duodenal ulcers, as well as gastric, adenocarcinoma.Virtually all infected individuals develop active chronic gastritis characterized by a continousinfiltration of neutrophils as well as mononuclear cells. LÄS MER

  4. 23. Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors

    Författare :Angela Äbelö; Mats Karlsson; Michael Looby; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

    Sammanfattning : Acid related diseases like GERD, duodenal-and gastric ulcers and H. Pylori-positive peptic ulcer disease are primarily managed by reducing gastric acidity. Irreversible proton pump inhibitors (PPIs) inhibit gastric acid secretion effectively throughout the day by irreversibly inhibiting the gastric proton pump, H+, K+-ATPase, in the parietal cells. LÄS MER

  5. 24. Persistent Helicobacter pylori infection and host response

    Författare :Sönke Andres; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Helicobacter pylori persistently colonizes the gastric mucosa of approximately one half of the world's population. Colonization always leads to chronic gastric inflammation, which may progress to peptic ulcer disease, gastric cancer or MALT lymphoma. The nature of H. pylori infection is determined by bacterial, host and environmental factors. LÄS MER

  7. 25. Mass spectrometry-based proteomic strategies applied to Helicobacter pylori. A Search for candidate vaccine antigens

    Författare :Elisabet Carlsohn; Göteborgs universitet; []
    Nyckelord :proteomics; mass spectrometry; Helicobacter pylori; membrane proteins; nano-liquid chromatography; subcellular fractionation;

    Sammanfattning : This thesis describes the development and refinement of proteomic strategies and the application of these on the human gastric pathogen H. pylori. The purpose was to identify proteins, and in particular membrane proteins, as potential targets for vaccine development. LÄS MER