Sökning: "bladder cancer KI"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden bladder cancer KI.

1. 1. Molecular progression and clonality or urinary bladder cancer

   Författare :Jari Louhelainen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The general aim of this work was to investigate the clonality of multifocal bladder tumours, chromosomal deletions and model the initiation-progression of bladder tumours at a molecular level using microsatellite analysis. In a population-based study, we found correlation between stage and grade and the prevalence of loss of heterozygosity (LOH) at all observed chromosome 13 loci and stage and grade, respectively. LÄS MER

3. 2. Familial risks for cancer with reference to lung cancer

   Författare :Xinjun Li; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Familial cancer; population-based; hereditary factors; familial risk; lung neoplasms.;

   Sammanfattning : Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a basis for clinical decisions and counseling, as well as guiding the identification of cancer-related genes. LÄS MER

4. 3. Tissue biomarkers in prostate cancer

   Författare :Sara Jonmarker Jaraj; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely immersed in formalin overnight. Formalin may also be injected into the prostate for improved fixation. LÄS MER

5. 4. Dietary heterocyclic amines and human cancer risk

   Författare :Katarina Augustsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :cancer; colon; rectum; bladder; kidney; human; heterocyclic amines; meat;

   Sammanfattning : Heterocyclic amines formed in meat during cooking are multi-site animal carcinogens and form DNA adducts in human tissues, but their relevance to human carcinogenesis has yet to be determined. The aim of this thesis was to investigate, by epidemiological methods, whether heterocyclic amines are responsible for part of the diet-related cancer burden in humans. LÄS MER

7. 5. Molecular cytogenetic investigations of chromosomal abnormalities in prostate and urinary bladder cancers

   Författare :Yi Pan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :prostate cancer; bladder cancer; FISH; SKY;

   Sammanfattning : Tumorigenesis is suggested to be caused by base pair mutations and chromosomal abnormalities leading to inactivation of tumor suppressor genes an activation of oncogenes. However, still it is not clear for the vast majority of these changes how they contribute to the tumorigenesis of the prostate and bladder cancers. LÄS MER