Sökning: "adipocyte determination"

Hittade 4 avhandlingar innehållade orden adipocyte determination.

  1. 1. Hormone-Sensitive Lipase - New roles in adipose tissue biology

    Författare :Kristoffer Ström; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinoid; adipogenesis; adipocyte determination; HSL; WAT;

    Sammanfattning : Obesity is defined as abnormal or excessive fat accumulation that may impair health, and increased knowledge about the enzymes controlling lipid metabolism is of great importance in order to combat this disease. Hormone-sensitive lipase (HSL) is a key enzyme in the mobilization of fatty acids from acylglycerols in adipocytes, but also plays important roles in other cell types. LÄS MER

  3. 2. Insulin and growth hormone : regulation of adipocyte metabolism during infancy and childhood

    Författare :Ashraf Fawzy Kamel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :human; rat; development; adipocytes; lipolysis; lipogenesis; glucose transport GLUT1; GLUT4; insulin; insulin receptor; growth hormone; growth hormone receptor microdialysis; obesity; Prader-Willi syndrome;

    Sammanfattning : The aim of the present investigation was to investigate the role of insulin and growth (GH) in adipose tissue metabolism during development. Lipolysis and lipogenesis were studied in isolated adipocytes from humans and rats of various ages. LÄS MER

  4. 3. Neurohormonal mechanisms in insulin resistance and type 2 diabetes

    Författare :Stina Lindmark; Claes-Göran Östenson; Umeå universitet; []
    Nyckelord :;

    Sammanfattning : Insulin resistance usually occurs early in the development of type 2 diabetes. An altered balance in the autonomic nervous system and in certain endocrine and inflammatory pathways, might contribute to the development of insulin resistance. LÄS MER

  5. 4. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression

    Författare :Per Antonson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Basic leucine zipper; CCAATEnhancer Binding Protein; CEBP; DNA binding protein; Gene expression; Transcription factor;

    Sammanfattning : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipper class of transcription factors with a total of 6 members having been identified in this family so far. This gene family has been mainly implicated in regulation of cell specific gene expression and differentiation. LÄS MER