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1. 1. The attenuation of the P53 response to DNA damage in rodent liver preneoplastic enzyme-altered foci

   Författare :Niklas Finnberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Enzyme-altered foci; p53; ATM; diethylnitrosamine; phenobarbital; liver; gene dosage;

   Sammanfattning : In connection with life-time bioassays in rodents, the liver is one of the organs most frequently affected. During the carcinogenic process, single preneoplastic hepatocytes develop into hepatocellular adenoma or carcinoma (HCC). LÄS MER