Sökning: "NF-kappa-B"
Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet NF-kappa-B.
1. Mechanisms of TRAIL- and Smac mimetic-induced cell death and phenotypical changes in breast cancer
Sammanfattning : .... LÄS MER
2. Repression of transcription factor NF-[kappa]B by glucocorticoids : a molecular mechanism for their anti-inflammatory and immuno-modulatory effects
Sammanfattning : It has been known since the late 1940s that glucocorticoids (GCs) possess anti-inflammatory activity. Their various uses in the clinic include treatment of, rheumatoid arthritis, asthma and AIM skin diseases and also as means for avoiding rejection during transplantation. LÄS MER
3. Inducible nitric oxide synthase : in vascular smooth muscle cells
Sammanfattning : Besides the constitutively expressed nitric oxide synthase (NOS) in endothelial cells, vascular smooth muscle cells (SMC) have the potential to express the inducible isoform of NOS (iNOS). Given the important effects of nitric oxide and the high output of this enzyme, expression of iNOS in SMC and its pathophysiological significance were investigated in the present study. LÄS MER
4. Human insulin-like growth factor binding protein-4 and -6 : gene structure and transcription regulation
Sammanfattning : Insulin-like growth factors (IGF-I and IGF-II) are among the more abundant growth factors isolated from bone tissue and are synthesized by various bone cells including osteoblasts. The activity of IGFs is controlled by a family of binding proteins (IGFBPs) divided into subfamilies depending on their individual affinity for IGFs. LÄS MER
5. Myocardial protection by hyperoxia
Sammanfattning : Oxygen is essential for normal respiration in aerobic organisms, and prolonged deficit of oxygen always has detrimental consequences.However, all aerobic life forms are faced with the threat of oxidation from molecular oxygen. LÄS MER