Sökning: "NADPH-oxidase"

Visar resultat 1 - 5 av 55 avhandlingar innehållade ordet NADPH-oxidase.

  1. 1. Human mononuclear phagocytes : Production of reactive oxygen species generated by the NADPH oxidase

    Författare :Agneta Johansson; Roger Sundler; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Human professional phagocytes constitute the first line of defence against invading microorganisms. With a membrane-bound enzyme system, the NADPH oxidase, these cells generate bactericidal metabolites. Activation of NADPH oxidase results in a generation of reactive oxygen species, e.g. LÄS MER

  3. 2. Inflammation in experimental neonatal brain injury and in a clinical study of preterm birth; involvement of galectin-3 and free radical formation

    Författare :Christina Doverhag; Göteborgs universitet; []
    Nyckelord :preterm labour; premature prelabour rupture of membranes; chorioamnionitis; hypoxia-ischemia; neonatal brain injury; NADPH oxidase; galectin-3; MMP-9; ascorbyl radicals; antioxidative capacity;

    Sammanfattning : Introduction; Intrauterine infection/inflammation is associated with preterm delivery (PTD) and severe neonatal morbidity. Inflammation is also important in the secondary neurotoxic cascade leading to perinatal brain injury. LÄS MER

  4. 3. Identification of galectins as novel inflammatory mediators

    Författare :Jenny Almkvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human neutrophils; NADPH-oxidase; Galectin-1; Galectin-3; priming; degranulation;

    Sammanfattning : The human neutrophils play important roles in the host defence against invading microorganisms. To eliminate bacteria or other invaders the neutrophils have to leave the bloodstream and cross the endothelium, migrate through the extracellular matrix towards the site of infection and phagocytose the prey to ultimately kill it. LÄS MER

  5. 4. Aspects of Regulation of GFR and Tubular Function in the Diabetic Kidney : Roles of Adenosine, Nitric Oxide and Oxidative Stress

    Författare :Patrik Persson; Fredrik Palm; Peter Hansell; Bengt Rippe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; diabetic nephropathy; glomerular filtration rate; renal blood flow; insulin; renal hemodynamics; micropuncture; oxygen; NADPH-oxidase; apocynin; streptozotocin; l-arginine; CGS21680; rats; mice; Physiology; Fysiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Diabetic nephropathy is the main cause for initiation of renal replacement therapy and early symptoms in patients include increased glomerular filtration rate (GFR), decreased oxygen tension and albuminuria, followed by a progressive decline in GFR and loss of kidney function. Experimental models of diabetes display increased GFR, decreased tissue oxygenation and nitric oxide bioavailability. LÄS MER

  7. 5. Recognition by leukocyte formyl peptide receptors. Promiscuous binding or pattern recognition?

    Författare :Johan Bylund; Göteborgs universitet; []
    Nyckelord :neutrophils; chemoattractant; FPRL1; NADPH-oxidase; LPS; priming; subcellular organelles; human; murine;

    Sammanfattning : Neutrophil granulocytes play an important role in the early stages of microbial infection. The neutrophils have to leave the blood stream and migrate out into the tissue where they phagocytose microbes and cell debris from damaged host tissues. LÄS MER