Sökning: "Breast neoplasms"

Visar resultat 11 - 15 av 16 avhandlingar innehållade orden Breast neoplasms.

1. 11. Malignancies associated with gynecological cancer : epidemiological and etiological aspects

   Författare :Kjell Bergfeldt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Neoplasms; second primary; ovarian cancer; breast cancer.;

   Sammanfattning : The aims of this thesis were to analyze the incidence and risk of second primary malignancies (SPM) in a Swedish cohort of gynecological cancer patients, to explore suggested risk factors associated with second primary malignancies in ovarian cancer patients, and to evaluate the risk of ovarian cancer in a cohort of breast cancer patients in relation to family history of breast or ovarian cancer. Incidence of second primary malignancies in 15,200 gynecologicaI cancer patients were investigated in a register-based study and compared to age- and calendar-specific incidence for women in the general population. LÄS MER

3. 12. Does cancer originate in utero?

   Författare :Magnus Kaijser; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Epidemiology; prenatal exposure delayed effects; breast neoplasms; testicular neoplasms; lung neoplasms; pregnancy; estrogens; estriol; low birth weight body weight; height; twins; matemal exposure; smoking; infant premature; small for gestational age.;

   Sammanfattning : The purpose of the present thesis was to evaluate Trichopoulos' hypothesis that breast cancer can originate in utero, and to examine the role of antenatal estrogen exposure in the etiology of testicular cancer. First, we used data from a Swedish-Norwegian cohort study on risk factors for small-for-gestational-age births to identify markers for antenatal estrogen exposure. LÄS MER

4. 13. Physical activity from the epidemiological perspective : measurement issues and health effects

   Författare :Ylva Trolle Lagerros; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Breast neoplasms; cohort studies; energy metabolism; epidemiologic methods; exercise; meta-analysis; mortality; questionnaires; review; validation studies; women;

   Sammanfattning : The aim of this thesis was to increase our understanding of links between physical activity and health. The relationships between physical activity and breast cancer risk and between current physical activity and overall mortality were examined. Additionally, a novel method was developed to measure physical activity in epidemiological studies. LÄS MER

5. 14. Familial risks for cancer with reference to lung cancer

   Författare :Xinjun Li; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Familial cancer; population-based; hereditary factors; familial risk; lung neoplasms.;

   Sammanfattning : Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a basis for clinical decisions and counseling, as well as guiding the identification of cancer-related genes. LÄS MER

7. 15. Exposures in utero and chronic disease : an alternative methodological approach

   Författare :Anna Hübinette; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cardiovascular disease; acute myocardial infarction; angina pectoris; breast neoplasms; birth weight; birth anthropometrics; twin study; epidemiology; etiology; risk factors; insulin-like growth factors; preeclampsia; longitudinal study.;

   Sammanfattning : The aims of this thesis were to evaluate maternal and birth characteristics as risk factors for breast cancer and cardiovascular disease later in life, and to assess maternal serum concentrations of insulin-like growth factors in pregnancies complicated by preeclampsia. Birth characteristics and risks of breast cancer were studied in a case-control study nested within the population-based Swedish Twin Register (Paper 1). LÄS MER