Sökning: "eicosanoids"

Visar resultat 1 - 5 av 38 avhandlingar innehållade ordet eicosanoids.

  1. 1. Eicosanoids in cancer : new therapeutic targets in neuroblastoma

    Författare :Agnes Rasmuson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer is one of the most common causes of death for both children and adults in developed countries. Neuroblastoma is a cancer of the sympathetic nervous system that affects infants and young children. Neuroblastoma tumors are the most common solid extracranial tumors in children and are also the most deadly. LÄS MER

  3. 2. Eicosanoids and exosomes : a link between macrophages and lung cancer

    Författare :Ana Lukic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic inflammation increases the risk of lung cancer. Macrophages (MO) are important players in inflammation, with regulatory and executive functions. Eicosanoids and exosomes can be both triggers and mediators of these functions. LÄS MER

  4. 3. Exploring eicosanoids as biomarkers in severe chronic rhinosinusitis with nasal polyps

    Författare :Axel Nordström; Maria Kumlin; Marie Svedberg; Mattias Jangard; Michael Ryott; Gunnar Nilsson; Sophiahemmet Högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Chronic rhinosinusitis (CRS) is one of the most common inflammatory chronic conditions, leading to a persistent nasal congestion, nasal discharge, and a loss of smell. Despite sinus surgery and frequent use of oral corticosteroids, a large proportion of individuals with CRS are difficult to treat and have recurrent inflammation. LÄS MER

  5. 4. Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense

    Författare :Xiao Tang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host. In humans, cathelicidins and defensins represent the major families of AMPs. LÄS MER

  7. 5. Clinical studies on the role of eicosanoids in the asthmatic airway inflammation

    Författare :Kameran Daham; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The underlying mechanisms in the asthmatic airway inflammation involve the interaction between different cells and mediators that consequently result in different clinical phenotypes. The aim of this thesis was to investigate the impact of inflammatory mediators, with emphasis on eicosanoids, on the inflammatory and functional airway responses under basal and triggered conditions in subjects with asthma, in particular ASA/NSAID-intolerant and allergic phenotypes. LÄS MER