Sökning: "contractility"

Visar resultat 11 - 15 av 86 avhandlingar innehållade ordet contractility.

1. 11. Cardiac Resynchronization Therapy Optimization : Comparison and Evaluation of Non-invasive Methods

   Författare :Elena Sciaraffia; Carina Blomström Lundqvist; Giuseppe Boriani; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiac resynchronization therapy; device optimization; left ventricular contractility; Cardiology; Kardiologi;

   Sammanfattning : The general purpose of this thesis was to investigate new cardiac resynchronization therapy (CRT) optimization techniques and to assess their reliability when compared to invasive measurements of left ventricular contractility (LV dP/dtmax).We first assessed whether cardiac output (CO) measured by trans-thoracic impedance cardiography could correctly identify the optimal interventricular (VV) pacing interval while using invasive measurements of LV dP/dtmax as reference. LÄS MER

3. 12. Integration of signalling in smooth muscle caveolae

   Författare :Yulia Shakirova; Cellulär biomekanik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveola; caveolin; detrusor; cavin; smooth muscle contractility; remodelling; NO; vascular dysfunction; smooth muscle; erectile dysfunction;

   Sammanfattning : Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis examine the role of caveolae in smooth muscle function. LÄS MER

4. 13. Effects of calcium on the in vitro contractility of some non-mammalian vertebrate myocardia during hypoxia, acidosis and temperature variations

   Författare :Gunnel Lagerstrand; Jönköping University; []
   Nyckelord :;

   Sammanfattning : .... LÄS MER

5. 14. Effects of ageing on contractility and myosin composition of rat and man skeletal muscles and muscle cells : with special reference to muscle adaptability

   Författare :Xiaopeng Li; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :ageing; hyperthyroidism; skeletal muscle; single skinned fibre; isometric twitch; slack test; shortening velociy; electrophoresis; myosin isoform; immunocytochemistry;

   Sammanfattning : The aims of this thesis were to characterize the effects of ageing on the contractile and biochemical properties of fast- and slow-twitch skeletal muscles at the whole muscle and single fibre level in an attempt to improve our understanding of the mechanisms underlying the age-related impairments of muscle fibres. Specific interest was in the adaptability of skeletal muscle and the regulation of speed of shortening at single-cell level in the rat and man. LÄS MER

7. 15. Cardiac function in experimental septic and non-septic conditions with special reference to the endothelin system

   Författare :David Konrad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :sepsis; cardiac; endothelin; endotoxin; levosimendan; contractility; diastolic; LVPVR.;

   Sammanfattning : Myocardial depression in sepsis has been intensely investigated for the past 30 years and still poses a considerable issue in the intensive care units. Both systolic and diastolic dysfunction is implicated, correlating with severity of illness and mortality The importance of the endothelin (ET) system in normal physiology has been extensively studied. LÄS MER