Sökning: "PTD"

Visar resultat 11 - 14 av 14 avhandlingar innehållade ordet PTD.

  1. 11. Enhancing T cell mediated immunity in DNA vaccination

    Författare :Jan Alvar Lindencrona; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA vaccination; CTL; T cell; IFN-gamma; anti-tumor immunity; HER-2 neu; Influenza; LCMV; Virus-Like Particles; murine models; adjuvants; immunotherapy;

    Sammanfattning : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. LÄS MER

  3. 12. Effects of influenza A virus infections and interferon-gamma on synapse formation and function in hippocampal neurons in culture

    Författare :Johan Brask; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Influenza A virus; hippocampal neurons; interferon-gamma; electrophysiology; synapses.;

    Sammanfattning : The central nervous system (CNS) can be the target for several infections that include those with RNA viruses. The parenchyma of the CNS is considered an immuneprivileged site since it is protected behind the blood-brain barrier, expresses no or only low levels of major histocompatibility complex (MHC) molecules and contains a paucity of antigenpresenting cells that prime an immune response. LÄS MER

  4. 13. Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery

    Författare :Maria Hallingström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amniotic fluid; biomarkers; cytokine; damage-associated molecular pattern; gestation; gestational duration; inflammation; labor; mid-trimester; multiplex; pregnancy clock; proteins; spontaneous preterm delivery; term delivery;

    Sammanfattning : Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal development, which regulate the onset of labor has previously been described. LÄS MER

  5. 14. Improving prognostication for patients with myelodysplastic syndromes

    Författare :Maria Creignou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background and aims: MDS constitute a heterogenous group of myeloid malignancies mainly characterized by dysfunctional hematopoiesis. Although cytopenia, dysplastic features and evidence of clonality are essential criteria for the diagnosis of all MDS, the several subtypes of the disease have a highly variable prognosis. LÄS MER