Sökning: "zoologisk"
Visar resultat 1 - 5 av 123 avhandlingar innehållade ordet zoologisk.
1. Epigenetic Control of Mammalian Development : Studies on an imprinting control region
Sammanfattning : A subset of autosomal genes is preferentially or exclusively expressed from one of the parental alleles. This phenomenon, termed genomic imprinting, is highlighted by the neighboring Igf2 and H19 genes, which are monoallelically expressed on opposite parental chromosomes. These features are governed by a 2. LÄS MER
2. A Comparative Study of Head Development in Mexican Axolotl and Australian Lungfish: Cell Migration, Cell Fate and Morphogenesis
Sammanfattning : The development of the vertebrate head is a complex process involving interactions between a multitude of cell types and tissues. This thesis describes the development of the cranial neural crest and of the visceral arch muscles in the head of two species. LÄS MER
3. Transcriptional Silencing in the Imprinted Igf2-H19 Loci: The Mystique of Epigenetics
Sammanfattning : Genomic imprinting marks a subset of autosomal loci expressed in parent of origin-dependent monoallelic expression in a non-Mendelian fashion. To restore totipotency and to reset the imprint according to the sex of the individual, the mark must be erased during germline development. LÄS MER
4. Epigenetic Regulation of Higher Order Chromatin Conformations and Gene Transcription
Sammanfattning : Epigenetic states constitute heritable features of the chromatin to regulate when, where and how genes are expressed in the developing conceptus. A special case of epigenetic regulation, genomic imprinting, is defined as parent of origin-dependent monoallelic expression. LÄS MER
5. Epigenetic Regulation of the H19 Chromatin Insulator in Development and Disease
Sammanfattning : The coordinated regulation of gene expression must be tightly controlled for normal development to occur. In mammals, this issue is further complicated by the requirement of both the maternal and paternal genomes for normal development, reflecting the fact that a subset of genes are monoallelically expressed depending on parental inheritance, a phenomenon known as genomic imprinting. LÄS MER