Sökning: "yeast"

Visar resultat 11 - 15 av 678 avhandlingar innehållade ordet yeast.

  1. 11. Engineered Yeast as Biocatalyst for Stereoselective reductions of Dicarbonyl Compounds

    Författare :Ted Johanson; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chiral; screening; process optimisation; metabolic engineering; dicarbonyl; biocatalysis; yeast; bioreduction; Biotechnology; Bioteknik;

    Sammanfattning : Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. LÄS MER

  3. 12. Bioreduction of Carbonyl Compounds to Chiral Alcohols by Whole Yeast Cells: Process Optimisation, Strain Design and Non-Conventional Yeast Screening

    Författare :Michael Katz; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bicyclic diketone; carbonyl; yeast; candida; cerevisiae; reductase; ketone; reduction; whole cell; YMR226c; YDR368w; Microbiology; bacteriology; virology; mycology; Biokemisk teknik; Biochemical technology; mykologi; virologi; Mikrobiologi; bakteriologi;

    Sammanfattning : Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. LÄS MER

  4. 13. Silencing and DNA double-strand break repair in budding yeast

    Författare :Andreas Kegel; Stefan Åström; Stephan Marcand; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Silencing; Reb1; DSB; NHEJ; Nej1; illegitimate recombination; yeast; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : Transcriptional silencing that makes large chromosomal domains inaccessible for the transcriptional apparatus is nucleated at DNA elements called silencers. In K.lactis a 102bp HMLα silencer was defined revealing three distinct protein-binding regions (A, B, and C) that were required for silencing of HMLα. LÄS MER

  5. 14. Adaptive divergence in fission yeast : From experimental evolution to evolutionary genomics

    Författare :Sergio Ivan Tusso Gomez; Jochen B.W. Wolf; Simone Immler; Roger K. Butlin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adaptation; divergence; selection; experimental evolution; genomics; genome evolution; population genetics; fission yeast; phenotypic variation; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : How adaptation and population differentiation occur is fundamental to understand the origin of biodiversity. Work in speciation alongside the increased ease of generating genomic data have allowed the exploration of genomic changes relevant to adaptation. LÄS MER

  7. 15. CRISPRi/a for investigating yeast tolerance to inhibitors in lignocellulosic hydrolysates

    Författare :Ibai Lenitz Etxaburu; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Lignocellulosic hydrolysates; ChIP-exo; Screening; Biosensor; Formic acid; Competitive growth assay; Yeast; Tolerance; CRISPRi a; Acetic acid;

    Sammanfattning : Saccharomyces cerevisiae has immense potential as a cell factory in various biotechnological processes where biomass from agricultural industry residues is used as feedstock. Nonetheless, the inhibitors released during the pretreatment of the biomass makes lignocellulosic hydrolysates a challenging substrate for microorganisms. LÄS MER