Sökning: "xiong"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet xiong.

  1. 1. What modulates telomere dynamics? : Inheritance, developmental effects, and physiological challenges

    Författare :Ye Xiong; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Telomere; Telomere dynamics; Telomere length; telomere inheritance; Zebra finch; Immune challenge; Heritability; Taenopygia guttata; Physiological parameter;

    Sammanfattning : Telomeres are the conservative sequence repeats located at the end of linear chromosomes that have been the focus of intensive research across many disciplines over the last four decades. They function as a cap to protect the chromosome ends from fusion to other chromosomes and to prevent chromosome degradation. LÄS MER

  3. 2. Visualising neurodegeneration in the living brain : Preclinical evaluation of PET radioligands

    Författare :Mengfei Xiong; Stina Syvänen; Sahar Roshanbin; Joakim Bergström; Per Borghammer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography PET ; Alzheimer s disease; Parkinson s disease; SV2A; neurodegeneration; immunotherapy; transgenic mice; Medicinsk vetenskap; Medical Science; Analytical Chemistry; Analytisk kemi; Pharmacology; Farmakologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : With an ageing population, the number of people suffering from Alzheimer’s disease (AD) and Parkinson’s disease (PD) escalates yearly. Pathological hallmarks of AD and PD include aggregated proteins and synaptic dysfunction. LÄS MER

  4. 3. Enhancing IT Systems Cyber Resilience through Threat Modeling : Cyber Security Analysis of Enterprise Systems and Connected Vehicles

    Författare :Wenjun Xiong; Robert Lagerström; Simon Hacks; Jelena Zdravkovic; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cyber Security; Threat Modeling; Attack Simulations; IT Systems; Security Analysis; Electrical Engineering; Elektro- och systemteknik;

    Sammanfattning : Information technology (IT) systems are growing in complexity and are becoming more and more connected. Such connected systems can increase flexibility and productivity while also introducing security threats. LÄS MER

  5. 4. Development of Novel Hydroporphyrins for Light Harvesting and Sensitising NIR Lanthanide Luminescence

    Författare :Ruisheng Xiong; Eszter Borbas; Christian Brückner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chlorin; hydroporphyrin; chlorophyll analogues; light harvesting; lanthanide luminescence; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : Chlorins, as the core structures of chlorophylls, have been extensively studied for harvesting solar energy, fluorescent imaging and photodynamic therapy against cancer. This thesis is concerned with design and synthesis of novel chlorins as antennae for harvesting light and sensitising near infrared lanthanide luminescence. LÄS MER

  7. 5. Novel Regulators of Brain Tumor Development : – From neural stem cell differentiation to in vivo models

    Författare :Anqi Xiong; Karin Forsberg Nilsson; Joanna Phillips; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; medulloblastoma; neural stem cell; heparanase; NRBP2; dog models; susceptibility;

    Sammanfattning : Malignant brain tumors are diseases with poor prognosis and/or severe long-term side effects of treatment. This thesis aimed to discover novel regulators in brain tumor development, based on studying neural stem cell and progenitor cell (NSPC) differentiation and using animal models to introduce new insights to mechanisms of human brain tumors. LÄS MER