Sökning: "x = o"

Visar resultat 1 - 5 av 368 avhandlingar innehållade orden x = o.

  1. 1. Electron and X-ray spectroscopic studies of free molecules

    Författare :Lars O. Werme; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  3. 2. Redesign of substrate specificity of glutathione transferase and glutathione reductase : Enzyme engineering by directed mutagenesis, phage-display selection and DNA shuffling

    Författare :Lars O. Hansson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Human glutathione transferase (GST) A1-1 was expressed in fusion with the phage gene IIIproduct and a library of phage-displayed GST mutants was constructed by randomization of fouractive-site residues. Variant GSTs were isolated by mechanism-based phage display selection, using an immobilized transition-state analog of a nucleophilic aromatic substitution (SNAr) reaction. LÄS MER

  4. 3. Cell death and signal transduction pathways in Alzheimer's disease : the role of presenilin 1

    Författare :Bogdan O Popescu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mutated presenilins (PSs) may cause familial Alzheimer's disease (FAD) by altering neuronal signal transduction pathways, by increasing AP production or by triggering a number of proapoptotic mechanisms. The present thesis explores mechanisms by which PSs regulate signal transduction and cell death with relevance to AD. LÄS MER

  5. 4. Novel Applications of Benziodoxole Reagents in the Synthesis of Organofluorine Compounds

    Författare :Nadia O. Ilchenko; Kálmán J. Szabó; Cristina Nevado; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; trifluoromethylation; hypervalent iodine; Togni reagent; difluorination; iodofluorination; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis concerns method development of new synthetic routes by applying electrophilic hypervalent iodine reagents, such as trifluoromethyl-benziodoxole (Togni reagent) and fluoro-benziodoxole. The first project involved the addition of an oxygen moiety and trifluoromethyl group across double and triple bonds (both groups derived from the hypervalent iodine reagent). LÄS MER

  7. 5. Relaxation and nanomechanical studies of the vickers residual stress field in glass

    Författare :Kwadwo O. Kese; Bill Bergman; Sture Hogmak; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; soda-lime glass; vickers residual stress field; nanoindentation; stress rekaxatuib; cube corner indenter; Materialvetenskap; Materials science; Teknisk materialvetenskap;

    Sammanfattning : The Vickers residual stress field (VRSF) in soda-lime glass results from the elastic-plastic contact event that takes place when a Vickers diamond pyramid is loaded onto the surface of the material in an indentation cycle. The importance of elastic-plastic indentation lies in the contact damage that it gives rise to in the surface of the glass. LÄS MER